Delirium in the Intensive Care Unit: Is Dexmedetomidine Effective?

Critical Care Nurse
Joelle UngarianKaren L Then

Abstract

Delirium in the intensive care unit affects approximately 30% of patients despite vigorous efforts to encourage the use of effective screening tools and preventive strategies. The success of pharmacological treatment of delirium remains equivocal; moreover, a paucity of research supports the use of atypical antipsychotic medications. However, dexmedetomidine appears to have a promising role in delirium management. This review includes an overview of the pathophysiology and types of delirium and describes 2 established tools used to screen for delirium. Published research related to the use of dexmedetomidine in the management of delirium is also discussed. The authors make recommendations for critical care nurses on dexmedetomidine use in the context of providing evidence-based nursing care to intensive care unit patients with delirium.

References

Apr 15, 2004·JAMA : the Journal of the American Medical Association·E Wesley ElyRobert S Dittus
Jun 11, 2004·Journal of Intensive Care Medicine·Eike MartinS T John Sum-Ping
Mar 23, 2006·Journal of the American Geriatrics Society·Josh F PetersonE Wesley Ely
Nov 15, 2006·Intensive Care Medicine·Sébastien OuimetYoanna Skrobik
Nov 28, 2007·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Brigit RobertsRichard Parsons
Dec 13, 2007·JAMA : the Journal of the American Medical Association·Pratik P PandharipandeE Wesley Ely
Feb 5, 2008·Critical Care Clinics·Max L GuntherE Wesley Ely
May 20, 2008·Expert Opinion on Drug Metabolism & Toxicology·Constantinos Chrysostomou, Carol G Schmitt
Jun 17, 2008·Critical Care : the Official Journal of the Critical Care Forum·Timothy D GirardE Wesley Ely
Feb 4, 2009·JAMA : the Journal of the American Medical Association·Richard R RikerUNKNOWN SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group
May 21, 2009·Critical Care : the Official Journal of the Critical Care Forum·Michael C ReadeRinaldo Bellomo
Jul 2, 2009·Psychosomatics·José R MaldonadoBruce A Reitz
Jun 15, 2010·Critical Care Nursing Clinics of North America·Jeffrey J Bruno, Mary Lou Warren
Nov 26, 2010·Critical Care : the Official Journal of the Critical Care Forum·Jorge I SalluhUNKNOWN Delirium Epidemiology in Critical Care Study Group
Dec 21, 2010·Current Opinion in Critical Care·Alessandro MorandiE Wesley Ely
Mar 29, 2011·Journal of Intensive Care Medicine·Neil A GilchristBruce Greenberg
Nov 1, 2011·Neurocritical Care·Erica H Z WangMary H H Ensom
Jan 25, 2012·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Dustin M Hipp, E Wesley Ely
Jun 9, 2012·Korean journal of anesthesiology·Soo-Bong Yu
Nov 28, 2012·Critical Care Clinics·Nathan E Brummel, Timothy D Girard
Dec 28, 2012·Critical Care Medicine·Juliana BarrUNKNOWN American College of Critical Care Medicine
Apr 18, 2013·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·David P ReardonPaul M Szumita
May 31, 2013·The Annals of Pharmacotherapy·Yoonsun Mo, Anthony E Zimmermann
Mar 3, 2015·Critical Care Nursing Clinics of North America·Jennifer Lacoske
Nov 18, 2015·BioMed Research International·S NelsonJ P Gagliardi
Mar 16, 2016·JAMA : the Journal of the American Medical Association·Michael C ReadeUNKNOWN Australian and New Zealand Intensive Care Society Clinical Trials Group
Mar 23, 2017·JAMA : the Journal of the American Medical Association·Yu KawazoeUNKNOWN Dexmedetomidine for Sepsis in Intensive Care Unit Randomized Evaluation (DESIRE) Trial Investigators

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