Delirium Monitoring in Neurocritically Ill Patients: A Systematic Review

Critical Care Medicine
Mayur B PatelE Wesley Ely

Abstract

The Society of Critical Care Medicine recommends routine delirium monitoring, based on data in critically ill patients without primary neurologic injury. We sought to answer whether there are valid and reliable tools to monitor delirium in neurocritically ill patients and whether delirium is associated with relevant clinical outcomes (e.g., survival, length of stay, functional independence, cognition) in this population. We systematically reviewed Cumulative Index to Nursing and Allied Health Literature, Web of Science, and PubMed. Inclusion criteria allowed any study design investigating delirium monitoring in neurocritically ill patients (e.g., neurotrauma, ischemic, and/or hemorrhagic stroke) of any age. We extracted data relevant to delirium tool sensitivity, specificity, negative predictive value, positive predictive value, interrater reliability, and associated clinical outcomes. Among seven prospective cohort studies and a total of 1,173 patients, delirium was assessed in neurocritically patients using validated delirium tools after considering primary neurologic diagnoses and associated complications, finding a pooled prevalence rate of 12-43%. When able to compare against a common reference standard, Diagnostic and Sta...Continue Reading

References

Jan 1, 1993·Critical Care Medicine·T P BleckC A Hansen
Jun 30, 2001·Intensive Care Medicine·N BergeronY Skrobik
Jan 18, 2002·Intensive Care Medicine·E W ElyS K Inouye
May 15, 2002·Critical Care Medicine·Thomas P Bleck
Mar 10, 2004·American Journal of Surgery·Richard D BlondellJames K Lukan
Apr 9, 2004·Critical Care Medicine·Eric B MilbrandtE Wesley Ely
Apr 15, 2004·JAMA : the Journal of the American Medical Association·E Wesley ElyRobert S Dittus
Sep 15, 2005·Neurocritical Care·Hilke OtterClaudia Spies
Nov 15, 2006·Intensive Care Medicine·Sébastien OuimetYoanna Skrobik
Apr 4, 2007·Intensive Care Medicine·Sébastien OuimetYoanna Skrobik
Feb 23, 2008·Critical Care : the Official Journal of the Critical Care Forum·John W DevlinYoanna Skrobik
Dec 20, 2008·American Journal of Surgery·Erik M AnglesErnest E Moore
Sep 12, 2009·American Journal of Respiratory and Critical Care Medicine·Margaret A PisaniPeter H Van Ness
Sep 29, 2009·Journal of Critical Care·Piero CerianaStefano Nava
Oct 16, 2009·Journal of Critical Care·Ulf GuentherChristian Putensen
May 18, 2010·Critical Care Medicine·Timothy D GirardE Wesley Ely
Sep 15, 2010·Critical Care Medicine·Yahya ShehabiUNKNOWN SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group
Apr 13, 2011·Journal of the Neurological Sciences·Marielle W A van RijsbergenPaul L M de Kort
May 13, 2011·American Journal of Respiratory and Critical Care Medicine·Maarten M van EijkArjen J Slooter
Jan 18, 2012·Critical Care Medicine·Yoanna Skrobik
May 11, 2012·Brain Injury : [BI]·Milena KostalovaStanislav Vohanka
May 23, 2012·Critical Care Medicine·Ary Serpa NetoArjen J Slooter
Jun 20, 2012·Critical Care Medicine·Max L GuntherUNKNOWN VISIONS Investigation, VISualizing Icu SurvivOrs Neuroradiological Sequelae
Jun 20, 2012·Critical Care Medicine·Ary Serpa Neto, Arjen J Slooter
Oct 16, 2012·Neurología : publicación oficial de la Sociedad Española de Neurología·B Ruiz BajoJ Martín Martínez
Dec 28, 2012·Critical Care Medicine·Juliana BarrUNKNOWN American College of Critical Care Medicine
Feb 22, 2013·The Journal of Trauma and Acute Care Surgery·Luca M BigatelloMoaven Razavi
Jul 31, 2013·Critical Care Medicine·Nathan E BrummelE Wesley Ely
Aug 31, 2013·Stroke; a Journal of Cerebral Circulation·Rosalind LeesTerence J Quinn
Oct 4, 2013·The New England Journal of Medicine·P P PandharipandeUNKNOWN BRAIN-ICU Study Investigators
Oct 10, 2013·American Journal of Respiratory and Critical Care Medicine·Andrew M NaidechE Wesley Ely
Jun 20, 2014·Critical Care : the Official Journal of the Critical Care Forum·Annemiek E WoltersArjen J C Slooter
Sep 24, 2014·The Journal of Trauma and Acute Care Surgery·Sarah B BryczkowskiAnne C Mosenthal
Nov 26, 2014·BMJ : British Medical Journal·Peter M C Klein KlouwenbergOlaf L Cremer
Dec 11, 2014·Critical Care Medicine·Sangeeta MehtaUNKNOWN Canadian Critical Care Trials Group
Jun 5, 2015·BMJ : British Medical Journal·Jorge I F SalluhRobert D Stevens

❮ Previous
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Citations

Oct 13, 2018·Critical Care Medicine·Richard R Riker, Gilles L Fraser
Sep 27, 2019·Stroke; a Journal of Cerebral Circulation·Robert C ShawTerence J Quinn
Apr 16, 2019·Current Opinion in Critical Care·Christina S BoncykChristopher G Hughes
Jun 23, 2020·Critical Care Medicine·Shawniqua Williams RobersonE Wesley Ely
Jul 23, 2020·Critical Care Explorations·Jennifer R MeeksFarhaan S Vahidy
Apr 10, 2019·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Cynthia A BautistaDaiWai M Olson
Nov 15, 2019·Current Treatment Options in Neurology·Michael E Reznik, Arjen J C Slooter
Nov 21, 2020·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Jiyeon KangJiwon Hong
Aug 4, 2020·Seminars in Respiratory and Critical Care Medicine·Matthew F MartE Wesley Ely
Apr 2, 2021·Journal of Critical Care·Fabian ReimannVerena Rass
Jun 12, 2021·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Gulsah KoseŞule Kurucu
Aug 17, 2021·Neurosurgical Review·P R KappenA P J E Vincent
Aug 17, 2021·Revue neurologique·E BouchereauC Legouy
Jul 5, 2021·Age and Ageing·Kaat GuldolfSylvie De Raedt

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