Delivering nanomedicines to patients: a practical guide

Nanomedicine : Nanotechnology, Biology, and Medicine
Mike A W EatonOlivier M A Fontaine

Abstract

This is a perspective on the current state of development of nanomedicines in Europe. The view is expressed that a much higher translational success rate could be achieved, with rewards for all stakeholders, if researchers understood the industrial decision points required for new drugs. Getting a drug through the clinic will not help patients unless it is developable by industry. This article is written in the hope that it will help researchers and SMEs to decide where they are in the established process, whether they are making progress and to determine what to do next. It attempts to map the early stages from ideation to first (time) in man (FIM). The field of nanomedicine has come a long way in the past decade. The overall dream of any researcher in this field remains the realization of concept to clinical product. In this paper, the authors outlined for the readers, the underlying problems and actions that need to be done, so that current challenges can be solved.

References

Apr 3, 2007·Nature Materials·Mike Eaton
Jun 28, 2011·Nanomedicine : Nanotechnology, Biology, and Medicine·Michael A W Eaton
Oct 12, 2011·Angewandte Chemie·Povl Krogsgaard-LarsenFlemming Besenbacher
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Oct 11, 2014·Angewandte Chemie·Harald F Krug

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Citations

Sep 16, 2015·Nanomedicine : Nanotechnology, Biology, and Medicine·Lisa BregoliAdriele Prina-Mello
Jan 17, 2016·Nanomedicine : Nanotechnology, Biology, and Medicine·Priya SatalkarDavid Shaw
Jul 15, 2015·Biochemical and Biophysical Research Communications·Sunil Shaunak
Sep 13, 2015·Biochemical and Biophysical Research Communications·Agnès PottierLaurent Levy
Nov 1, 2015·Biochemical and Biophysical Research Communications·Christoph Alexiou, Bengt Fadeel
Nov 1, 2015·Biochemical and Biophysical Research Communications·Esther H ChangDong Soo Lee
Oct 9, 2015·Nanomedicine·Ghazal PourGashtasbi
Sep 17, 2015·Science and Engineering Ethics·Priya SatalkarDavid M Shaw
Nov 9, 2016·Acta Biomaterialia·Carina PeresHelena F Florindo
Dec 21, 2018·Journal of Drug Targeting·Harivardhan Reddy Lakkireddy, Didier V Bazile
Nov 18, 2018·Histochemistry and Cell Biology·Gudrun C Thurner, Paul Debbage
Nov 5, 2016·The AAPS Journal·Henry HavelMaggie Liu
Oct 24, 2018·Frontiers in Bioengineering and Biotechnology·Ylea Vlamidis, Valerio Voliani
May 26, 2021·Expert Opinion on Drug Delivery·Eder Lilia Romero, Maria Jose Morilla
Jul 25, 2021·Drug Delivery and Translational Research·Snežana ĐorđevićMaría J Vicent
Dec 1, 2017·Bioconjugate Chemistry·Domenico CassanoValerio Voliani
Aug 24, 2021·Expert Opinion on Therapeutic Patents·Jabson Herber Profiro de OliveiraJosé Lamartine Soares-Sobrinho
Aug 28, 2021·International Journal of Molecular Sciences·Gudrun C ThurnerPaul Debbage
Aug 14, 2020·Bioconjugate Chemistry·Serge MignaniJean-Pierre Majoral

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