PMID: 6403727Jan 1, 1983Paper

Delivery of vitamins A, D, and E in total parenteral nutrition solutions

JPEN. Journal of Parenteral and Enteral Nutrition
J GillisP Pencharz

Abstract

The ward delivery of fat-soluble vitamins in parenteral nutrition solutions was simulated in a laboratory situation. Radioactively labeled vitamins A, D, and E were used in tracer studies to follow their nonradioactive counterparts during addition to a parenteral solution and subsequent passage through a standard infusion set. Using this quick convenient method, it was possible to monitor delivery over an entire 24-hour infusion period. Average recovery for vitamins A, D, and E was 31%, 68% and 64%, respectively. From comparison of various sampling sites during the experimental period, it seems clear that the fat-soluble vitamins appear to adhere to the bag and tubing. In light of these findings, we suggest a reexamination of the method of solubilization of fat soluble vitamins and of the materials used in the manufacture of clinical infusion equipment.

References

Jun 1, 1980·The Journal of Pediatrics·R A CannonE W Fonkalsrud
Oct 1, 1980·Annals of Internal Medicine·L HowardB Wolf

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Citations

Oct 1, 1988·Baillière's Clinical Gastroenterology·A Shenkin
Feb 1, 1988·The Journal of Pediatrics·R C EdwardsM Thompson
Feb 1, 1987·Archives of Disease in Childhood·D Van Zoeren-GrobbenH M Berger
Mar 22, 2008·International Journal of Pharmaceutics·Sogol KangarlouYaghob Gholipour
Oct 1, 1985·Current Problems in Surgery·J J Reilly, A L Gerhardt
Aug 1, 1986·Journal of Clinical and Hospital Pharmacy·G B DahlH J Tengborn
Sep 1, 1984·Journal of Clinical and Hospital Pharmacy·M C Allwood
Jun 1, 1984·Journal of Clinical and Hospital Pharmacy·M C Allwood
Dec 1, 1984·Journal of Clinical and Hospital Pharmacy·K NordfjeldV Gaunø Jensen
Sep 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·C D McGeeK N Jeejeebhoy
Jul 1, 1987·JPEN. Journal of Parenteral and Enteral Nutrition·A C BaratN L McIntosh
Apr 16, 2004·Journal of Pediatric Gastroenterology and Nutrition·Peter J PorcelliEugene Adcock
May 1, 1994·JPEN. Journal of Parenteral and Enteral Nutrition·G B DahlU K Bergström
Mar 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·D LabadariosG S Shephard
May 1, 1993·JPEN. Journal of Parenteral and Enteral Nutrition·S T Robbins, A B Fletcher
Sep 1, 1984·JPEN. Journal of Parenteral and Enteral Nutrition·J S BertinoT C Halpin
Mar 1, 1996·JPEN. Journal of Parenteral and Enteral Nutrition·A B BallingerM J Farthing
Sep 5, 2002·European Journal of Clinical Nutrition·C HaasB Koletzko
Mar 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·S Jacobson
Jul 1, 1987·Drug Intelligence & Clinical Pharmacy·J M Mirtallo, T Oh

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