Delusions of alien control in the normal brain

S J BlakemoreC D Frith


Delusions of alien control, or passivity experiences, are symptoms associated with schizophrenia in which patients misattribute self-generated actions to an external source. In this study hypnosis was used to induce a similar misattribution of self-generated movement in normal, healthy individuals. Positron Emission Tomography (PET) was employed to investigate the neural correlates of active movements correctly attributed to the self, compared with identical active movements misattributed to an external source. Active movements attributed to an external source resulted in significantly higher activations in the parietal cortex and cerebellum than identical active movements correctly attributed to the self. We suggest that, as a result of hypnotic suggestion, the functioning of this cerebellar-parietal network is altered so that self-produced actions are experienced as being external. These results have implications for the brain mechanisms underlying delusions of control, which may be associated with overactivation of the cerebellar-parietal network.

Associated Clinical Trials


Jan 1, 1991·Experimental Brain Research·M P DeiberR S Frackowiak
Jul 1, 1990·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K J FristonR S Frackowiak
Apr 30, 1971·Nature·L WeiskrantzC Darlington
Sep 29, 1995·Science·D M WolpertM I Jordan
Feb 9, 1999·Journal of Cognitive Neuroscience·P RainvilleD D Price
Oct 3, 1999·Brain : a Journal of Neurology·A SiriguM Jeannerod
Oct 3, 1999·Brain : a Journal of Neurology·T MimaH Shibasaki
Oct 8, 1999·Journal of Cognitive Neuroscience·S J BlakemoreD M Wolpert
Dec 22, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·T Bundick, M Spinella
Jul 27, 2000·The American Journal of Psychiatry·S M KosslynD Spiegel
Jan 11, 2001·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·H Burton, R J Sinclair
Feb 24, 2001·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C D FrithD M Wolpert
Mar 17, 2001·Nature Reviews. Neuroscience·J Driver, C Frith
Jul 4, 2001·Neuroreport·S J BlakemoreD M Wolpert
Aug 10, 2001·Neuroreport·K O BusharaB R Brooks
Oct 31, 2001·Trends in Cognitive Sciences·Daniel M. WolpertJ Randall Flanagan
Mar 15, 2002·Neuroreport·Gabriella BottiniGiuseppe Vallar
Sep 1, 1993·Journal of Motor Behavior·R C MiallJ F Stein
Nov 1, 1996·Neural Networks : the Official Journal of the International Neural Network Society·D M. Wolpert, R C. Miall
Jan 1, 1963·The International Journal of Clinical and Experimental Hypnosis·R E SHOR, E C ORNE
Sep 1, 2004·Consciousness and Cognition·Patrick HaggardDavid A Oakley
Mar 31, 2006·Cognitive Neuropsychiatry·D A Oakley
Sep 1, 1998·Trends in Cognitive Sciences·D M WolpertM Kawato

❮ Previous
Next ❯


Feb 8, 2006·Archives of General Psychiatry·Boris BirmaherMartin Keller
Oct 27, 2004·Experimental Brain Research·E L SantarcangeloL Sebastiani
Mar 16, 2013·European Archives of Psychiatry and Clinical Neuroscience·C HeinischM Brüne
Jun 26, 2007·Brain Topography·Hitoshi KatayamaDietrich Lehmann
Nov 26, 2013·Consciousness and Cognition·George Van DoornMark Symmons
May 15, 2003·Current Opinion in Neurobiology·Sarah Jayne Blakemore, Chris Frith
Mar 3, 2004·Consciousness and Cognition·F de Vignemont, P Fourneret
Dec 4, 2008·Nature Reviews. Neuroscience·Paul C Fletcher, Chris D Frith
Apr 4, 2006·The International Journal of Clinical and Experimental Hypnosis·Justin D WinkelMichael R Nash
Dec 1, 2006·The International Journal of Clinical and Experimental Hypnosis·David A OakleyPeter W Halligan
Aug 30, 2008·The International Journal of Clinical and Experimental Hypnosis·Akira R O'ConnorRochelle E Cox
May 29, 2010·The International Journal of Clinical and Experimental Hypnosis·Victoria GaleaMichael R Pierrynowski
Nov 22, 2011·The International Journal of Clinical and Experimental Hypnosis·Etzel CardeñaKieko Kochi
Nov 22, 2011·The International Journal of Clinical and Experimental Hypnosis·Burkhard PeterMaria Hagl
Jul 9, 2008·Cognitive Neuropsychology·Giancarlo CarliEnrica L Santarcangelo
Aug 1, 2007·Anthropology & Medicine·Simon Dein, Roland Littlewood
Jan 12, 2010·Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD)·Paul F Dell
Jul 18, 2008·Social Neuroscience·Roger D Newman-NorlundHarold Bekkering
Jul 22, 2008·Cerebral Cortex·Mina N EvangeliouHelen E Savaki
May 12, 2007·Schizophrenia Bulletin·Peter Williamson
Aug 30, 2008·Schizophrenia Bulletin·Flavie A V Waters, Johanna C Badcock
Jun 23, 2010·Journal of Negative Results in Biomedicine·Bruno R SouzaMarco A Romano-Silva
Nov 21, 2012·PloS One·Julio Fernando PeresAndrew Newberg
Mar 11, 2011·The International Journal of Clinical and Experimental Hypnosis·Thilo HinterbergerUlrike Halsband
Jul 28, 2013·Social Cognitive and Affective Neuroscience·Vera U LudwigHenrik Walter
Dec 27, 2013·Social Cognitive and Affective Neuroscience·Katharina D PaulyUte Habel
Jun 29, 2014·Neuroscience Research·Yudai Takarada, Daichi Nozaki
Apr 4, 2006·The International Journal of Clinical and Experimental Hypnosis·Giancarlo CarliEnrica L Santarcangelo
May 2, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Fiona ToalDeclan G M Murphy
Jan 19, 2007·Psychotherapy and Psychosomatics·Christian H RöderDavid E J Linden
Apr 3, 2012·Behavioural Brain Research·Katharina MüllerRüdiger J Seitz
Jul 15, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Bauke M de Jong
Mar 2, 2010·Consciousness and Cognition·David A Oakley, Peter W Halligan
May 1, 2015·The American Journal of Clinical Hypnosis·Mathieu Landry, Amir Raz
May 12, 2009·Trends in Cognitive Sciences·David A Oakley, Peter W Halligan
Oct 24, 2007·Cognition·Elisabeth Pacherie
Nov 1, 2008·Neuropsychologia·Paul M JenkinsonSimon J Ellis

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Consciousness and Cognition
Patrick HaggardD A Oakley
Proceedings of the National Academy of Sciences of the United States of America
H SzechtmanC Nahmias
Consciousness and Cognition
Sarah-Jayne Blakemore
© 2022 Meta ULC. All rights reserved