PMID: 15374322Sep 1, 1993Paper

Dementia, learning and the P300 paradigm

Archives of Gerontology and Geriatrics
U Wranek, G Ladurner

Abstract

This investigation was designed to measure learning effects in demented patients, using psychophysiological methods. Twenty-five patients with vascular dementia and 25 age-matched controls were investigated with a P300 and reaction-time paradigm. The repetition of the cognitive process discriminating between different sizes of circles led to a significant decrease in P300 latency and in reaction time. It was therefore concluded that such a paradigm is able to measure learning effects, and also that vascularly-demented patients can improve their performance on such tasks.

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