PMID: 9434673Jan 22, 1998Paper

Dementias that present with and without posterior cortical features: an important clinical distinction

Journal of the American Geriatrics Society
D R Royall, M Polk

Abstract

There are distinct qualitative differences between the dementias that present with and without posterior cortical features. These can be utilized in dementia assessment. This paper reviews the validity and potential utility of a dichotomy based on generalized cortical (Type 1) versus isolated frontal system pathology (Type 2). These syndromes are associated with distinct differentials and problem behaviors. They may also result in different caregiving burdens or treatment responses. Alzheimer's disease (AD) is by far the most common cause of the Type 1 syndrome. Type 2 presentations select for potentially reversible non-AD conditions. Common cognitive screening instruments are insensitive to Type 2 cases. However, the Type 1/Type 2 distinction can be made reliably using qualitative clinical rating scales. We will review these instruments and discuss their application in clinical settings.

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Citations

Apr 21, 2010·The International Journal of Neuroscience·Randolph W ParksPeter W R Woodruff
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Jan 26, 2005·Journal of the American Geriatrics Society·Donald R RoyallMarsha J Polk
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Feb 14, 2004·Journal of the American Geriatrics Society·Donald R RoyallMarsha J Polk
Jan 20, 2006·Journal of the American Geriatrics Society·Donald R Royall
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Apr 6, 2004·Clinics in Geriatric Medicine·David S Geldmacher
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May 4, 2004·CNS Spectrums·Thomas Benke, Elfriede Karner

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