Demographic and Clinical Predictors of Trait Impulsivity in Parkinson's Disease Patients

Parkinson's Disease
Maddeson RileyRyan S Anderton

Abstract

Impulsive behaviour has become increasingly recognised as a neuropsychiatric complication of Parkinson's disease (PD). Thought to be a product of compromised cognitive control, the spectrum of impulsive behaviours in PD ranges from cognitive disinhibition to impulse control disorders (ICDs). At present, there are no indicators for trait impulsivity in PD. The objective of the current study was to identify demographic and clinical predictors of susceptibility to trait impulsivity in a cohort of PD patients. The current study assessed impulsivity using the Barratt Impulsiveness Scale 11 (BIS-11) in a cohort of 87 PD patients. General linear models (GLMs) were used to identify clinical and demographic variables predictive of heightened BIS-11 second-order attentional and nonplanning subscale scores. Male gender, no history of smoking, postsecondary education, and heightened disease severity were predictive of increased BIS-11 attentional scores (p < 0.05). Similarly, male gender, after secondary education, and disease severity were predictive of increased BIS-11 nonplanning scores (p < 0.05). Contrary to previous reports, dopaminergic medication use was not a significant determinant of either BIS-11 subscale scores. Several demogr...Continue Reading

References

Nov 1, 1995·Journal of Clinical Psychology·J H PattonE S Barratt
Jan 1, 1997·Journal of Substance Abuse·T L Waldeck, L S Miller
Mar 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·S GauggelT-A Feghoff
Nov 25, 2006·Brain : a Journal of Neurology·S Rivaud-PéchouxB Gaymard
Feb 14, 2007·Archives of Neurology·Valerie VoonMateusz Zurowski
Dec 11, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Ioannis U IsaiasAngelo Antonini
May 7, 2010·The Neurologist·Gülay KenangilEthem Erginöz
May 12, 2010·Archives of Neurology·Daniel WeintraubAnthony E Lang
Jan 12, 2011·Psychological Bulletin·Catharine P CrossAnne Campbell
Feb 12, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Angelo AntoniniPaolo Barone
Feb 23, 2011·Neuron·Jeffrey W DalleyTrevor W Robbins
Mar 19, 2011·Annals of Neurology·Valerie VoonMark Stacy
Apr 13, 2011·Human Brain Mapping·Zheng YeThomas F Münte
Jun 7, 2011·Experimental Brain Research·Ignacio ObesoMarjan Jahanshahi
Nov 1, 2011·Parkinsonism & Related Disorders·Iracema LeroiAlistair Burns
Jul 26, 2012·Current Gerontology and Geriatrics Research·David J AhearnIracema Leroi
Jan 28, 2014·PloS One·Cristina NombelaJames B Rowe
Jun 5, 2014·Brain : a Journal of Neurology·Angie A KehagiaTrevor W Robbins
Mar 23, 2017·Journal of the Neurological Sciences·Tess EvansRyan S Anderton

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Citations

Oct 31, 2019·Parkinson's Disease·Ashani JeyadevanRyan S Anderton
May 30, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Fabio GiovannelliMassimo Cincotta

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