PMID: 8596257Apr 3, 1996Paper

Demographic determinants of hepatitis C virus seroprevalence among blood donors

JAMA : the Journal of the American Medical Association
E L MurphyG J Nemo

Abstract

To measure demographic determinants of hepatitis C virus (HCV) seroprevalence among blood donors in the United States. Cross-sectional epidemiological study. Five blood centers in different regions of the United States. A total of 862,398 consecutive volunteer blood donors with one or more nonautologous donations from March 1992 through December 1993. Demographic data collection, serological screening with second-generation anti-HCV enzyme immunoassay, and confirmation with anti-HCV recombinant immunoblot. There were 3126 donors with at least one blood donation confirmed HCV-seropositive, for a crude prevalence of 3.6 per 1000. Age-specific HCV seroprevalence rose from 0.5 per 1000 donors younger than 20 years to a maximum of 6.9 per 1000 in donors aged 30 to 39 years and declined in older age groups. There was interaction between age and educational attainment, with 30- to 49-year-olds with less than a high school diploma at highest risk of HCV infection (odds ratio [OR], 33.0; 95% confidence interval [CI], 23.0 to 47.2 compared with those younger than 30 years with a bachelor's degree or higher degree). Other independent risk factors for HCV seropositivity included male sex (OR, 1.9; 95% CI, 1.8 to 2.1), black race (OR, 1.7; ...Continue Reading

Citations

Oct 19, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Y YazdanpanahE Bouvet
Apr 28, 2004·Infectious Diseases in Obstetrics and Gynecology·Youyin ChoyPeter G McGovern
Jan 22, 2008·American Journal of Epidemiology·Anne M GuiltinanEdward L Murphy
Jul 14, 2010·The Journal of Infectious Diseases·Edward L MurphyUNKNOWN Retrovirus Epidemiology Donor Study
Mar 6, 2002·Journal of Viral Hepatitis·M I Memon, M A Memon
Jun 8, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Anne F CelonaMaurizio Bonacini
Mar 8, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·E L MurphyG J Nemo
Mar 17, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·M Charlton
Sep 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M CharltonJ Hoofnagle
Apr 2, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Abhijit ChowdhuryDebendra Nath Guha Mazumder
Jan 15, 2013·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Kerrilynn CarneyFritz Francois
Aug 1, 1997·The Journal of Pediatrics·M M JonasA B Middleman
Aug 25, 2004·Gastroenterology Clinics of North America·Lorna M Dove
Aug 28, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ryan M ThomasDavid H Van Thiel
Jun 14, 2014·Liver International : Official Journal of the International Association for the Study of the Liver·Engy Mohamed El-GhitanyAzza G Farghaly
Apr 16, 1999·The Journal of the American Dental Association·J A Gillcrist
Mar 13, 2016·Journal of Medical Virology·Engy M El-GhitanyEkram W Abd El-Wahab
Oct 26, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R SreekumarM R Charlton
Oct 4, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Michael Charlton
Nov 1, 2001·Clinics in Liver Disease·D L Thomas
Nov 27, 2002·Journal of Occupational and Environmental Medicine·Diane J MundtKenneth A Mundt
Aug 31, 2002·Journal of Gastroenterology and Hepatology·Seyed Moayed AlavianSadegh Masarrat
Sep 17, 2008·European Journal of Gastroenterology & Hepatology·Jean-François CadranelDominique Capron
May 22, 2003·Transfusion·B WangUNKNOWN Retrovirus Epidemiology Donor Study
Sep 24, 2004·Transfusion·Lakkana ThaikrueaKenrad E Nelson
Jan 10, 2003·Transfusion·George B SchreiberUNKNOWN Retrovirus Epidemiology Donor Study

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