Demographic predictors of active tuberculosis in people migrating to British Columbia, Canada: a retrospective cohort study

CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
Lisa A RonaldJames C Johnston

Abstract

Canadian tuberculosis (TB) guidelines recommend targeting postlanding screening for and treatment of latent tuberculosis infection (LTBI) in people migrating to Canada who are at increased risk for TB reactivation. Our objectives were to calculate robust longitudinal estimates of TB incidence in a cohort of people migrating to British Columbia, Canada, over a 29-year period, and to identify groups at highest risk of developing TB based on demographic characteristics at time of landing. We included all individuals (n= 1 080 908) who became permanent residents of Canada between Jan. 1, 1985, and Dec. 31, 2012, and were resident in BC at any time between 1985 and 2013. Multiple administrative databases were linked to the provincial TB registry. We used recursive partitioning models to identify populations with high TB yield. Active TB was diagnosed in 2814 individuals (incidence rate 24.2/100 000 person-years). Demographic factors (live-in caregiver, family, refugee immigration classes; higher TB incidence in country of birth; and older age) were strong predictors of TB incidence in BC, with elevated rates continuing many years after entry into the cohort. Recursive partitioning identified refugees 18-64 years of age from countrie...Continue Reading

Citations

Feb 7, 2019·Journal of Travel Medicine·Christina Greenaway, Francesco Castelli
Jun 28, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Katie D DaleJustin T Denholm
Jun 7, 2019·PLoS Medicine·Jonathon R CampbellKevin Schwartzman
Jun 20, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph H PuyatJames C Johnston
Nov 7, 2019·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Kristina Langholz KristensenMarie Norredam
Jun 16, 2018·International Journal of Environmental Research and Public Health·Alexandra JablonkaMartin Wetzke
Mar 12, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lisa A RonaldJames C Johnston
Jul 4, 2021·American Journal of Epidemiology·Jonathon R Campbell, Kevin Schwartzman

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