PMID: 590943Dec 1, 1977

Demonstration of 9-O-acetyl-N-acetylneuraminic acid in brain gangliosides from various vertebrates including man

Hoppe-Seyler's Zeitschrift für physiologische Chemie
J HaverkampJ F Vliegenthart

Abstract

Ganglioside fractions were isolated from brains of man, cow, horse, pig, sheep, cat, rabbit, rat, chicken and codfish. The acylneuraminic acid residues, liberated from these gangliosides by treatment with dilute aqueous acid or neuraminidase, were analysed by the thin-layer chromatography and combined gas-liquid chromatography/mass spectrometry. Small amounts (up to 20%) of 9-O-acetyl-N-acetylneuraminic acid, and in bovine and porcine brain gangliosides also traces of N-glycoloylneuraminic acid, were found in addition to N-acetylneuraminic acid.

References

Jun 1, 1975·Hoppe-Seyler's Zeitschrift für physiologische Chemie·S NeesR Schauer
Jan 18, 1976·Biochimica Et Biophysica Acta·R VehR Schauer
Oct 1, 1972·Journal of Neurochemistry·R H McCluer, B W Agranoff
Jul 14, 1970·Biochimica Et Biophysica Acta·I IshizukaH Wiegandt
Sep 1, 1963·Journal of Neurochemistry·L Svennerholm

Citations

Feb 1, 1993·Clinical Biochemistry·M Crook
Jan 1, 1984·Neurochemistry International·S SonninoH Rahmann
Feb 2, 1982·Biochimica Et Biophysica Acta·J P KamerlingM Wember
Jun 1, 1995·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·K Becker, H Rahmann
Oct 29, 1987·Biochemical and Biophysical Research Communications·C Mandal, S Basu
Mar 13, 2015·Molecular Neurobiology·Massimo AureliS Sonnino
Oct 25, 2003·European Journal of Clinical Nutrition·B Wang, J Brand-Miller
May 1, 1988·Journal of Cellular Biochemistry·J T Hutchins, C L Reading
Jun 1, 1980·Journal of Neurochemistry·S K GrossR H McCluer

Related Concepts

Brain Chemistry
Chromatography, Gas-Liquid
Gangliosides
Neuraminidase
Sialic Acids
Mass Spectrometry

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