PMID: 179579Apr 23, 1976

Demonstration of adenylate cyclase activity in human red blood cell ghosts

Biochimica Et Biophysica Acta
S B RodanR I Sha'afi


The presence of adenylate cyclase (ATP pyrophosphate-lyase (cyclizing) EC activity was demonstrated in human erythrocyte ghosts and was found to be around 3 pmol adenosine 3',5'-monophosphate (cyclic AMP) - 2 h-1 - mg-1 protein. This enzymatic activity is strongly stimulated by NaF and 5'-guanylimidodiphosphate, is slightly stimulated by epinephrine, norepinephrine, isoproterenol, and prostaglandin E1 and is inhibited by calcium. The hormone stimulation is not potentiated by 5'-guanylylimidodiphosphate.


Jul 1, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Madelyn S HansonR S Sprague
Aug 1, 1979·The Journal of Clinical Investigation·T Tsukamoto, M Sonenberg
Apr 1, 1982·The Journal of Clinical Investigation·E BoginJ Smith
Sep 1, 1979·Archives of Biochemistry and Biophysics·E L ThomasM Morrison
Nov 14, 1979·Biochemical and Biophysical Research Communications·P A KienerE W Westhead
Nov 16, 1979·Biochimica Et Biophysica Acta·M J NelsonW H Huestis
Jan 1, 1982·Biochemical Pharmacology·Georg Sager
Jan 1, 1978·Upsala Journal of Medical Sciences·G RonquistP Ericsson
Oct 15, 1985·Biochemical Pharmacology·Georg Sager, S Jacobsen
Jul 15, 1979·Biochemical Pharmacology·Georg Sager, S Jacobsen
Jan 1, 1978·Journal of Supramolecular Structure·G FairbanksV P Patel
Jan 1, 1978·Journal of Cellular Physiology·M WacholtzR I Sha'afi
Dec 28, 1979·Biochemical and Biophysical Research Communications·C BeaumontG Schapira
Dec 16, 2017·Journal of Cellular Physiology·Georg SagerOle-Martin Fuskevaag
Jan 1, 1979·Annals of the New York Academy of Sciences·G A RodanR I Sha'afi
May 17, 2008·Journal of Materials Science. Materials in Medicine·Rupak M RajacharCecilia M Giachelli
May 16, 2012·The Journal of Physiology·M L Ellsworth, R S Sprague
Jul 16, 2010·Pharmacological Reports : PR·Shaquria P AdderleyMadelyn S Hanson
Sep 8, 2001·American Journal of Physiology. Cell Physiology·R S SpragueA J Lonigro
Jul 1, 1985·The American Journal of Physiology·E E SusanniC Rosendorff

Related Concepts

Calcium [EPC]
Cyclic AMP
Norepinephrine, (+, -)-Isomer
Cyclic Adenosine Monophosphate Measurement
Epinephrine Measurement

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