PMID: 602509Jan 1, 1977Paper

Demonstration of an agglutination-like nature of haptoglobins against streptococci with T4-antigen through the examination of umbilical cord sera

Zentralblatt für Gynäkologie
O Prokop, W Köhler

Abstract

The determinability of haptoglobin types is correlated with the titers of agglutination against streptococci carrying the T4 antigen. If the haptoglobin types in cord-sera cannot be determined (as a result of the physiological binding of haptoglobins) the agglutination reaction fails or the titers are greatly diminished. The dimorphism, which was found in sera of adults, can be demonstrated in cord sera, too, if they can be typed. It is concluded that the observed reaction between Hp 2-2 and Hp 2-1 sera with T4-streptococci is caused by the haptoglobin itself.

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