PMID: 7085428Apr 1, 1982Paper

Demonstration of failure of body plethysmography in airway obstruction

Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
D O RodensteinC Francis

Abstract

To demonstrate the role of extrathoracic airways in the overestimation of lung volumes by body plethysmography in airway obstruction, we induced in six normal subjects an artificial airway stenosis by inflating a balloon in the lower trachea. We measured thoracic gas volume in a body plethysmograph simultaneously from mouth pressure (Pm) vs. plethysmographic volume (Vbox) (TGVm) and from esophageal pressure (Pes) vs. Vbox (TGVes). During control measurements there was no difference between TGVm and TGVes (P greater than 0.1) in any subject. Balloon inflation (B) resulted in a significant (P less than 0.01) decrease of specific airway conductance (sGaw) from a mean value of 0.199 +/- 0.66 (SD) to 0.025 +/- 0.01 cmH2O-1 . s-1. TGVm significantly (P less than 0.02) exceeded TGVes in every subject (mean diff 1.24 +/- 0.56 liters) and Pm lagged behind Pes. In two subjects studied at different levels of airway obstruction we found a significant (P less than 0.05) correlation between TGVm-TGVes difference and sGaw. Bypassing the extrathoracic airways by a cuffed endotracheal tube resulted in each case in a degree of airway obstruction comparable to that during balloon inflation (sGaw 0.019 +/- 0.004 cmH2O-1 . s-1), but no difference b...Continue Reading

Citations

Sep 30, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·M Oswald-MammosserEvelyne Lonsdorfer-Wolf
Jan 1, 1991·Pediatric Pulmonology·A L Coates, J Stocks
Mar 5, 1992·The New England Journal of Medicine·H L Manning
May 1, 1992·Medical & Biological Engineering & Computing·P Gizdulich
Jul 16, 2005·Experimental Lung Research·Andrew HoffmanEdward Ingenito
Sep 3, 1999·Journal of the Royal Society of Medicine·C K van der Ent, P L Brand
Apr 29, 2006·Journal of Applied Physiology·Tibor Z JánosiZoltán Hantos
Aug 26, 2006·Journal of Applied Physiology·D C Stănescu
Oct 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·T J Gal

Related Concepts

Choking
Airway Resistance
False Positive Reactions
Intubation, Intratracheal
Plethysmography, Whole Body
Chest

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