Demonstration of Kathon CG in some commercial products

Contact Dermatitis
B GruvbergerS Fregert

Abstract

The preservative Kathon CG has become one of the most common sensitizers. It has, however, been difficult to explain the sensitization and to assess the clinical relevance of the contact allergy, partly due to lack of specification of the preservative in products. A high-performance liquid chromatography method was used to demonstrate Kathon CG in 123 commercial products of both "leave on" and "rinse off" types. 38 of these contained Kathon CG in the range of 1-15 ppm of active ingredients. There were no differences between "leave on" and "rinse off" products concerning the relative number of products containing Kathon CG and the concentrations of the preservative.

References

Feb 1, 1986·Contact Dermatitis·B BjörknerK Persson

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Citations

Feb 1, 1988·Journal of the American Academy of Dermatology·A C de Groot, J W Weyland
Apr 4, 1998·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·B Gruvberger, M Bruze
May 1, 1990·Journal of the American Academy of Dermatology·R L RietschelJ C Mitchell
Oct 1, 1989·Journal of the American Academy of Dermatology·S Fregert
Apr 1, 1987·Contact Dermatitis·M BruzeK Persson
Feb 1, 1986·Contact Dermatitis·B BjörknerK Persson
Mar 1, 1988·Contact Dermatitis·A Tosti
Nov 1, 1988·Contact Dermatitis·A F Fransway
May 1, 1988·Contact Dermatitis·E CroninC L Meneghini
Sep 1, 1988·Contact Dermatitis·A C de GrootJ M Conemans
Mar 1, 1987·The British Journal of Dermatology·A C de Groot, J D Bos
Sep 1, 1995·Contact Dermatitis·L Fernández de CorrèsM D Del Pozo
Aug 1, 1991·Contact Dermatitis·G Färm, J E Wahlberg
May 1, 1990·Contact Dermatitis·A HassonL Condé-Salazar
Mar 1, 1990·Contact Dermatitis·S C Rastogi
Jan 1, 1996·Environmental and Molecular Mutagenesis·T H ConnorK M Connor
Sep 1, 1988·Contact Dermatitis·S Massarotti, F A Fairweather

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