Demonstration of proton-transfer reaction time-of-flight mass spectrometry for real-time analysis of trace volatile organic compounds

Analytical Chemistry
Robert S BlakePaul S Monks

Abstract

A proton-transfer reaction mass spectrometer based on time-of-flight mass spectrometry is described. This instrument couples a radioactive ion source and drift tube with a reflectron time-of-flight mass spectrometer. Volatile organic compounds in the gas phase with concentrations at the parts per billion by volume level can be detected in a matter of seconds, and crucially, the multichannel data acquisition in TOF-MS means that this detection sensitivity is available in all mass channels simultaneously. The typical mass resolution (m/Deltam) is in excess of 1000. The performance of the instrument is demonstrated using urban air measurements and a linear response/calibration test.

References

Jul 8, 2003·Rapid Communications in Mass Spectrometry : RCM·Peter PrazellerMichael Alexander

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Citations

May 17, 2011·Analytical and Bioanalytical Chemistry·Carolina Muñoz-GonzálezM Ángeles Pozo-Bayón
Apr 28, 2012·Analytical and Bioanalytical Chemistry·Aude VesinHenri Wortham
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Jun 21, 2008·Journal of Agricultural and Food Chemistry·María-Angeles Pozo-BayónGary A Reineccius

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