PMID: 7520273Apr 1, 1994Paper

Demonstration of sweat allergy in cholinergic urticaria

Journal of Dermatological Science
J AdachiA Yamatodani

Abstract

Twenty patients with cholinergic urticaria, 11 sex- and age-unmatched patients with acute or chronic urticaria and 20 sex- and age-matched non-atopic control subjects were skin tested with autologous sweat. All cholinergic urticaria patients showed positive immediate-type skin reactions at 2(0)-2(9) dilutions of sweat (geometric mean of maximal positive dilutions +/- S.D. was 2(4.6 +/- 2.6), while in acute and chronic urticaria only three patients showed positive reactions at low dilutions (two 2(0) and one 2(1)) and none of 20 controls showed positive reactions. Prausnitz-Küstner (P-K) tests performed with the serum and sweat from six patients were all positive at 2(3)-2(8) dilutions. Percent histamine release from peripheral leukocytes of five patients challenged with the standard sweat samples was significantly higher than in five control subjects. Histamine release from leukocytes of the patient on sweat challenging was abandoned by acid treatment of leukocytes. Leukocytes, from a healthy subject sensitized with the patient's serum, released histamine on sweat challenging. These results seem to indicate that cholinergic urticaria patients have a type I allergy to their own sweat.

References

Jun 1, 1975·The Journal of Allergy and Clinical Immunology·A P KaplanM A Beaven
Jan 1, 1979·The Journal of Allergy and Clinical Immunology·R W SiglerA P Kaplan
Jan 1, 1978·The British Journal of Dermatology·C A Commens, M W Greaves
Nov 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C E GrattanM W Greaves
Apr 1, 1987·Archives of Dermatology·J L Jorizzo

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Citations

Aug 7, 2009·Current Allergy and Asthma Reports·Tastuya HorikawaChikako Nishigori
Jun 6, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Konstantinos PetalasChristina Gratziou
Apr 27, 2000·Allergy·M W Greaves
May 20, 2014·Journal of Dermatological Science·Sabine AltrichterMarcus Maurer
Nov 23, 2013·Immunology and Allergy Clinics of North America·Marina AbajianMarcus Maurer
Jul 9, 2010·The Journal of Investigative Dermatology·Yu SawadaYoshiki Tokura
Oct 12, 2013·Journal of Veterinary Internal Medicine·G LorchK K Isler
Jan 11, 2013·The British Journal of Dermatology·A Sheraz, S Halpern
Mar 5, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·S NakamizoK Kabashima
Apr 11, 2000·The Journal of Allergy and Clinical Immunology·M Greaves
Mar 3, 2011·Allergology International : Official Journal of the Japanese Society of Allergology·Takeshi KozaruChikako Nishigori
Oct 25, 2012·Allergology International : Official Journal of the Japanese Society of Allergology·Toshinori BitoYoshiki Tokura
Jan 25, 2014·Allergology International : Official Journal of the Japanese Society of Allergology·Makiko HiragunMichihiro Hide
May 14, 2016·The Australasian Journal of Dermatology·Hee Joo Kim, Min-Geol Lee
Jun 22, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·S AltrichterM Maurer
Nov 25, 2000·Hospital Medicine·J Powell, S Powell
Jun 3, 2014·Annals of Dermatology·Jung Eun KimJun Young Lee
Jan 5, 1996·The Journal of Biological Chemistry·G HennigJ Behrens
Sep 6, 2017·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A AsadyS Altrichter
Jun 10, 2020·Clinical and Translational Allergy·Sabine AltrichterMarcus Maurer
Apr 7, 2017·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Atsushi FukunagaChikako Nishigori
May 4, 2004·Immunology and Allergy Clinics of North America·John P Dice

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