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Demonstration of tumor inhibiting properties of a strongly immunostimulating low-molecular weight substance. Comparative studies with ifosfamide on the immuno-labile DS carcinosarcoma. Stimulation of the autoimmune activity for approx. 20 days by BA 1, a N-(2-cyanoethylene)-urea. Novel prophylactic possibilities

Arzneimittel-Forschung

Sep 1, 1975

M Ardenne, P G Reitnauer

PMID: 22

Abstract

A report is given on the recent discovery of outstanding immunological properties in BA 1 [N-(2-cyanoethylene)-urea] having a (low) molecular mass M = 111.104. Experiments in 214 DS carcinosarcoma bearing Wistar rats have shown that BA 1, at a dosage of only about 12 percent LD50 (150 m...read more

Mentioned in this Paper

Antineoplastic Agents
Research
Cyclophosphamide
Immunologic Deficiency Syndromes
N-(2-cyanoethylene)urea
Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Carmol
Drug Tolerance
Neoplasms
Tumor Lysis Syndrome
13
3
5
26
9
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Demonstration of tumor inhibiting properties of a strongly immunostimulating low-molecular weight substance. Comparative studies with ifosfamide on the immuno-labile DS carcinosarcoma. Stimulation of the autoimmune activity for approx. 20 days by BA 1, a N-(2-cyanoethylene)-urea. Novel prophylactic possibilities

Arzneimittel-Forschung

Sep 1, 1975

M Ardenne, P G Reitnauer

PMID: 22

DOI:

Abstract

A report is given on the recent discovery of outstanding immunological properties in BA 1 [N-(2-cyanoethylene)-urea] having a (low) molecular mass M = 111.104. Experiments in 214 DS carcinosarcoma bearing Wistar rats have shown that BA 1, at a dosage of only about 12 percent LD50 (150 m...read more

Mentioned in this Paper

Antineoplastic Agents
Research
Cyclophosphamide
Immunologic Deficiency Syndromes
N-(2-cyanoethylene)urea
Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Carmol
Drug Tolerance
Neoplasms
Tumor Lysis Syndrome
13
3
5
26
9

Similar Papers Found In These Feeds

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