Dendritic cell immunotherapy for HIV infection: from theory to reality

Immunotherapy
Telma Miyuki OshiroAlberto José da Silva Duarte

Abstract

Knowledge concerning the immunology of dendritic cells (DCs) accumulated over the last few decades and the development of methodologies to generate and manipulate these cells in vitro has made their therapeutic application a reality. Currently, clinical protocols for DC-based therapeutic vaccine in HIV-infected individuals show that it is a safe and promising approach. Concomitantly, important advances continue to be made in the development of methodologies to optimize DC acquisition, as well as the selection of safe, immunogenic HIV antigens and the evaluation of immune response in treated individuals.

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Citations

Sep 21, 2011·Immunology and Cell Biology·Jose M Martinez-NavioRafael Franco
May 15, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Maria T Rodriguez-PlataJavier Martinez-Picado

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Methods Mentioned

BETA
leukapheresis

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