Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis.

Medical Hypotheses
Mona Kamal SaadeldinAhmed Abdellatif

Abstract

Immunotherapy is the newest approach to combat cancer. It can be achieved using several strategies, among which is the dendritic cell (DC) vaccine therapy. Several clinical trials are ongoing using DC vaccine therapy either as a sole agent or in combination with other interventions to tackle different types of cancer. Immunotherapy can offer a potential treatment to coronavirus disease 2019 (COVID-19) the worst pandemic facing this generation, a disease with deleterious effects on the health and economic systems worldwide. We hypothesize that DC vaccine therapy may provide a potential treatment strategy to help combat COVID-19. Cancer patients are at the top of the vulnerable population owing to their immune-compromised status. In this review, we discuss DC vaccine therapy in the light of the body's immunity, cancer, and newly emerging infections such as COVID-19 in hopes of better-customized treatment options for patients with multiple comorbidities.

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Citations

Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aliye Gediz ErturkTuba Yildirim

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Datasets Mentioned

BETA
GM-CSF

Methods Mentioned

BETA
oncotherapy

Clinical Trials Mentioned

NCT02018458
NCT01042535
NCT00082641
NCT01876212
NCT00289341
NCT00345293
NCT00085436
NCT00103116
NCT00617409

Software Mentioned

RECIST

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