Dengue fever complicated with Guillain-Barré syndrome: a case report and review of the literature

Journal of Medical Case Reports
Chamara DalugamaIndika Bandara Gawarammana

Abstract

Dengue is an arboviral infection classically presenting with fever, arthralgia, headache, and rashes. It is hyperendemic in Sri Lanka and has a major impact on health. Neurological complications of dengue fever are rare but have been reported in the literature. A 60-year-old Sri Lankan man presented with a history of fever, arthralgia, and generalized malaise of 2 days duration. A diagnosis of dengue was confirmed with leukopenia, thrombocytopenia, and positive NS1 antigen done on day 2 without evidence of hemoconcentration. On admission, our patient had weakness of the bilateral lower limbs, which progressed in an ascending pattern involving both upper limbs and neck muscles, requiring assisted ventilation. Electromyography confirmed a demyelinating polyneuropathy and cerebrospinal fluid showed albumincytological dissociation. He was treated with intravenous immunoglobulins and made an uneventful recovery. Subsequently, his immunoglobulin M test result for dengue virus was positive. Guillain-Barré syndrome is a rare but possible neurological sequel following dengue fever. In regions where dengue is hyperendemic, screening for dengue illness may be important in patients presenting with acute flaccid paralysis.

References

Jun 1, 1992·Acta Paediatrica Japonica; Overseas Edition·S K Hendarto, S R Hadinegoro
Mar 1, 2000·Journal of Neuroimmunology·R A HughesK J Smith
Sep 25, 2003·Neurology·R A C HughesUNKNOWN Quality Standards Subcommittee of the American Academy of Neurology
Jun 12, 2008·Arquivos de neuro-psiquiatria·Cristiane Nascimento SoaresMarzia Puccioni-Sohler
Nov 17, 2010·Nature Reviews. Microbiology·Maria G GuzmanRosanna W Peeling
Feb 22, 2012·Annals of Indian Academy of Neurology·Rajesh VermaHardeep Singh Mehrotra
Aug 5, 2015·Neurology India·Ravindra Kumar GargKiran Preet Malhotra
Dec 20, 2016·Arquivos de neuro-psiquiatria·Yara Dadalti FragosoTalyta Grippe

❮ Previous
Next ❯

Citations

Oct 31, 2018·Current Infectious Disease Reports·Annelies Wilder-Smith
Oct 17, 2019·Journal of Travel Medicine·Manon VougaMilos Stojanov
Aug 20, 2019·Journal of Travel Medicine·Scott Halstead, Annelies Wilder-Smith
Feb 19, 2019·International Journal of Preventive Medicine·Rouzbeh R GhafouriSamad E J Golzari
Mar 2, 2021·Frontiers in Neurology·Thomas LangerakEric C M van Gorp
Jul 14, 2021·Journal of the Peripheral Nervous System : JPNS·Debprasad DuttaVasanthapuram Ravi

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

BMC Research Notes
Dissanayake Mudiyanselage Priyantha Udaya Kumara RalapanawaWidana Arachilage Thilak Ananda Jayalath
Neurosciences : the Official Journal of the Pan Arab Union of Neurological Sciences
Ayman A Aleyadhy, Gamal M Hassan
Journal of the Indian Medical Association
Chandra Mohan SharmaShailesh Dixit
Revista Da Sociedade Brasileira De Medicina Tropical
Raimundo N Q LeãoPedro F C Vasconcelos
© 2022 Meta ULC. All rights reserved