Dengue fever in Pakistan: a paradigm shift; changing epidemiology and clinical patterns

Perspectives in Public Health
Zahra HaiderMalik Asif Humayun

Abstract

Dengue fever has huge public health implications and affects over 100 million people worldwide. This review pictures the current situation of Dengue in Pakistan and presents a review of published literature. Pakistan has seen recurrent epidemics of Dengue Fever recently. Unfortunately, these epidemics are becoming more severe in their clinical manifestation. Pakistan experienced large epidemics of dengue fever during 2008, 2010 and 2011 affecting thousands of people and claiming hundreds of deaths. A comparison of data during these epidemics indicates a shift from mild to a more severe disease, which could be interpreted as an epidemiologic transition pattern in the country. Expansion of Dengue in Pakistan seems to be multifactorial, including the climate change, frequent natural disasters, vector resistance to insecticides and lack of resources. This highlights the need for rigorous vector control. Continuing education of primary care physicians is crucial for early appropriate management to reduce mortality.

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Citations

Dec 8, 2016·PLoS Neglected Tropical Diseases·John M HumphreyLaith J Abu-Raddad
Nov 7, 2015·Perspectives in Public Health·Rosalind Stanwell-Smith
May 13, 2020·The American Journal of Tropical Medicine and Hygiene·Sulistyawati SulistyawatiÅsa Holmner
Sep 5, 2019·International Journal of Environmental Research and Public Health·Toqeer AhmedMiklas Scholz
Nov 16, 2020·Transactions of the Royal Society of Tropical Medicine and Hygiene·Mohammad Jahid HasanDavid Gozal
Jan 16, 2017·Kidney International·Emmanuel A Burdmann, Vivekanand Jha

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