PMID: 10325319May 15, 1999Paper

Density and molecular epidemiology of Aspergillus in air and relationship to outbreaks of Aspergillus infection

Journal of Clinical Microbiology
A LeendersH A Verbrugh

Abstract

After five patients were diagnosed with nosocomial invasive aspergillosis caused by Aspergillus fumigatus and A. flavus, a 14-month surveillance program for pathogenic and nonpathogenic fungal conidia in the air within and outside the University Hospital in Rotterdam (The Netherlands) was begun. A. fumigatus isolates obtained from the Department of Hematology were studied for genetic relatedness by randomly amplified polymorphic DNA (RAPD) analysis. This was repeated with A. fumigatus isolates contaminating culture media in the microbiology laboratory. The density of the conidia of nonpathogenic fungi in the outside air showed a seasonal variation: higher densities were measured during the summer, while lower densities were determined during the fall and winter. Hardly any variation was found in the numbers of Aspergillus conidia. We found decreasing numbers of conidia when comparing air from outside the hospital to that inside the hospital and when comparing open areas within the hospital to the closed department of hematology. The increase in the number of patients with invasive aspergillosis could not be explained by an increase in the number of Aspergillus conidia in the outside air. The short-term presence of A. flavus can...Continue Reading

References

Mar 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M A Pfaller
Mar 1, 1990·Journal of Clinical Microbiology·R BoomJ van der Noordaa
Jun 1, 1995·The Journal of Hospital Infection·R J HayJ M Goodley
Jun 1, 1995·Journal of Clinical Microbiology·A van BelkumH Koeleman
Jan 1, 1994·The Journal of Hospital Infection·J M GoodleyR J Hay
Apr 1, 1994·Clinical Microbiology Reviews·A van Belkum
Mar 1, 1994·Journal of Clinical Microbiology·H GirardinJ P Latgé
Nov 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·V T Andriole
Aug 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J N MaslowR D Arbeit
Nov 1, 1995·International Journal of Biometeorology·D W Li, B Kendrick
Feb 1, 1996·Journal of Clinical Microbiology·A LeendersH Verbrugh

❮ Previous
Next ❯

Citations

Nov 3, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J R PerfectUNKNOWN Mycoses Study Group
Sep 25, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Theresa HahnPhilip L McCarthy
Oct 26, 2000·Hospital Medicine·M EllisB de Pauw
Sep 5, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Brock D LutzMark M Huycke
Sep 17, 2008·Mycoses·H A de ValkJ F G M Meis
Jan 19, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Paraskevi PanagopoulouEmmanuel Roilides
Apr 23, 2009·The Journal of Antimicrobial Chemotherapy·Jacques F Meis
Mar 20, 2010·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·UNKNOWN Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut (RKI)
Jun 23, 2010·Mycopathologia·Brandon J Webb, Holenarasipur R Vikram
Nov 12, 2010·Medical Mycology·Lies M E VanheeTom Coenye
Sep 12, 2012·Current Opinion in Pulmonary Medicine·Jennifer J SpeirsJeffrey M Beekman
Jan 17, 2014·Journal of Medical Microbiology·Claudia CafarchiaDomenico Otranto
Oct 6, 2016·Medical Mycology·Maria Carla GreppiJean-Luc Cadoré
Feb 18, 2003·Pest Management Science·H Alastair McCartneyElaine Ward
Apr 20, 2002·Current Opinion in Infectious Diseases·J. Peter Donnelly
Sep 8, 2010·Medical Mycology·Marie-Christine NicollePhilippe Vanhems
Sep 11, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·V BergeronN Laudinet
Feb 9, 2010·Medical Mycology·Ricardo AraujoLeonor Gusmão
Aug 21, 2010·Letters in Applied Microbiology·C D VieiraL de Macêdo Farias
Jun 4, 2014·Mycopathologia·Safiatou Niaré-DoumboStéphane Ranque
Jan 7, 2006·Medical Mycology·Marta Feldmesser
Apr 10, 2014·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Julia D BurcoMichael H Ziccardi
Sep 25, 2007·Eukaryotic Cell·Tobias M Hohl, Marta Feldmesser
Nov 28, 2001·Current Infectious Disease Reports·David W. WarnockBrent A. Lasker
Dec 10, 2016·Indian Journal of Medical Microbiology·S M RudramurthyA Chakrabarti
Apr 9, 2001·Molecular and Cellular Probes·P Cruz-PerezL D Stetzenbach
May 16, 2001·Molecular and Cellular Probes·P Cruz-PerezL D Stetzenbach
Mar 23, 2007·Journal of Clinical Microbiology·J M BainF C Odds
Oct 10, 2002·The Journal of Allergy and Clinical Immunology·Harriet A Burge
Oct 9, 2004·Journal of Clinical Microbiology·Patricio GodoyArnaldo Lopes Colombo
Apr 28, 2001·Journal of Clinical Microbiology·S BertoutUNKNOWN European Research Group on Biotype and Genotype of Aspergillus

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aspergillosis

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.