PMID: 3745523Aug 1, 1986Paper

Density of the microflora in hand eczema before and after topical treatment with a potent corticosteroid

Journal of the American Academy of Dermatology
E J NilssonM L Hjörleifsson

Abstract

Twenty patients with hand eczema were studied with the use of quantitative bacteriologic cultures before and after successful topical treatment with a potent corticosteroid. One sample was taken from the most pronounced eczematous lesion, a second from skin affected with only erythema, and a third from clinically normal skin. Before quantitative bacteriologic analysis, the different species were combined into three main groups: Staphylococcus aureus, other aerobes, and anaerobes. Before treatment, S. aureus colonized the most pronounced eczematous lesion in eighteen of twenty patients and exceeded 10(5) cfu/cm2 in fifteen of twenty patients. The geometric mean count of S. aureus before treatment was significantly higher in eczema (10(4.8) cfu/cm2) than in erythema (10(3.4) cfu/cm2) and significantly higher in erythema than in normal skin (10(1.7) cfu/cm2). The density of other aerobes and anaerobes was similar in the three sampling sites. After treatment, the mean count of S. aureus was significantly reduced at all three sampling sites, and the densities became equal. Treatment did not affect the mean count of other aerobes or anaerobes.

References

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Citations

Dec 29, 2007·Clinical Reviews in Allergy & Immunology·Yu-Tsan LinBor-Luen Chiang
Jan 18, 2007·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Shuo-Hsun HungBor-Luen Chiang
Aug 21, 2003·American Journal of Clinical Dermatology·Jann Lübbe
Aug 29, 2014·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·K ParanthamanR Puleston
May 7, 2004·Contact Dermatitis·Kristiina AlankoLasse Kanerva
Jul 7, 2009·The British Journal of Dermatology·P HaslundT Agner
Apr 30, 2015·American Journal of Clinical Dermatology·Dimitar AntonovPeter Elsner
May 20, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S MerneliusC D Anderson
May 22, 2018·The Journal of Dermatological Treatment·Yue ChenWeimin Shi
Nov 19, 2004·The British Journal of Dermatology·A AlomarUNKNOWN European Working Group on Atopic Dermatitis
Aug 11, 2020·The Australasian Journal of Dermatology·Marius RademakerLi-Chuen Wong
Oct 1, 1994·The British Journal of Dermatology·J F StalderP Litoux
Mar 1, 1989·Journal of the American Academy of Dermatology·R R Roth, W D James

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