PMID: 8946367Oct 1, 1996Paper

Density resolution in quantitative computed tomography of foam and lung

Medical Physics
G J KemerinkJ M van Engelshoven

Abstract

This study was performed to assess density resolution in quantitative computed tomography (CT) of foam and lung. Density resolution, a measure for the ability to discriminate materials of different density in a CT number histogram, is normally determined by quantum noise. In a cellular solid, variations in mass in the volumes sampled by CT cause an additional degradation of density resolution by the linear partial volume effect. The sample volume, which is directly related to spatial resolution, can be varied by choosing different section thicknesses and reconstruction filters. Several polyethene (PE) foams, as simple models of lung tissue, and five patients were investigated using various sample volumes. For the uniform PE foams, density resolution could be directly determined as the full width at half maximum of CT number histograms. Density resolution for foams with cell sizes of 0.8-1.5 mm was dominated by effects caused by the limited sample size, not by quantum noise. The relative magnitudes of density resolution could roughly be explained with a model for a hypothetic random cellular solid. Since lungs are not of uniform density, analysis of patient data was more complicated. A combined convolution least-squares fit proc...Continue Reading

Citations

Feb 3, 2011·European Journal of Nuclear Medicine and Molecular Imaging·Gerrit J KemerinkGerrit J J Teule
Feb 19, 2009·European Radiology·Edoardo CavigliMario Mascalchi
Oct 16, 2004·Investigative Radiology·Berend C Stoel, Jan Stolk
Nov 24, 2005·Investigative Radiology·M Els BakkerBerend C Stoel
Dec 26, 2001·American Journal of Respiratory and Critical Care Medicine·Y NakanoJ C Hogg
Jan 14, 2009·Proceedings of the American Thoracic Society·Harvey O Coxson
Mar 19, 2009·Medical Physics·Zachary H LevineDiana N Zeiger
Apr 13, 2010·Academic Radiology·Bruno HochheggerJosé S Moreira
Feb 20, 2007·Respiratory Medicine·Suzanne MarshRichard Beasley
Jul 24, 2007·Respiratory Medicine·Jan StolkBerend C Stoel
Nov 14, 2016·International Journal of Computer Assisted Radiology and Surgery·Stefano DiciottiBernardo Innocenti
Jan 6, 1999·Medical Physics·G J KemerinkJ M van Engelshoven
Mar 25, 2011·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Bruno HochheggerJose Silva Moreira
Dec 5, 1997·Journal of Computer Assisted Tomography·G J KemerinkJ M van Engelshoven
Jan 31, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Igor PelizzoneEnrico Parmigiani
May 23, 2018·Journal of Applied Clinical Medical Physics·Thomas C LarsenHan Wen
Feb 11, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·L BertaA Torresin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.