Dental erosion in mice with impaired salivary gland function

Acta Odontologica Scandinavica
Amela TulekAmer Sehic

Abstract

Objective: Salivary flow rate exerts an essential impact on the development and progression of dental erosion. In this work, the experimental dental erosion in non-obese diabetic (NOD) mice with reduced salivary flow rate was induced, and the erosive effect of acidic drinks on their dentition was studied.Material and methods: Three acidic drinks (sports drink, cola light drink and sugar containing cola drink) were given to adult NOD mice (groups: N = 11) as the only drink for 6 weeks. Two control groups were included; wild type and NOD control (groups: N = 9). Experimental and control (water) teeth were dissected out and observed by scanning electron microscopy (SEM). Mandibular first molars were subsequently embedded in Epon, ground transversely, observed again by SEM, and the enamel thickness and tooth height were measured.Results: Mandibular molars were considerably more eroded than maxillary molars. The erosive process started at the top of the cusps and subsequently extended in the cervical, mesio-distal, and pulpal direction. Erosive lesions were evident in increased succession from sports drink, cola light to cola drink exposed mandibular molars, with the lingual tooth height being approximately 23%, 26%, and 37% lower, ...Continue Reading

References

Jun 1, 1991·Journal of Dental Research·V K JärvinenO P Heinonen
Jan 1, 1980·Jikken dobutsu. Experimental animals·S MakinoY Tochino
Feb 1, 1997·Community Dentistry and Oral Epidemiology·J Tenovuo
Mar 28, 1998·The Anatomical Record·S P LyngstadaasS Risnes
Jun 17, 1999·Nature Medicine·M A Atkinson, E H Leiter
Sep 10, 1999·Clinical Immunology : the Official Journal of the Clinical Immunology Society·S YamanoP C Fox
Jul 5, 2002·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·S ChaM G Humphreys-Beher
Mar 5, 2003·Advances in Experimental Medicine and Biology·M G Humphreys-BeherA B Peck
Dec 20, 2003·Caries Research·A LussiD Zero
Nov 25, 2004·European Journal of Oral Sciences·Ann-Katrin JohanssonDowen Birkhed
Sep 20, 2005·International Dental Journal·Domenick T Zero, Adrian Lussi
Feb 1, 2012·European Journal of Oral Sciences·Ann-Katrin JohanssonAnders Johansson
Mar 27, 2012·BMC Oral Health·Aida MulicAnne B Skaare
Jul 6, 2012·Acta Odontologica Scandinavica·Aida MulicAnne B Skaare
Nov 10, 2012·Journal of Applied Oral Science : Revista FOB·Marília Afonso Rabelo BuzalafMelissa Thiemi Kato
Nov 22, 2012·Acta Odontologica Scandinavica·Thorbjörg JensdottirAllan Bardow
Jun 19, 2013·Caries Research·N ZwierG J Truin
Jul 6, 2014·Monographs in Oral Science·Adrian Lussi, Thiago S Carvalho
Jul 6, 2014·Monographs in Oral Science·Thomas Jaeggi, Adrian Lussi
Jul 6, 2014·Monographs in Oral Science·Michele E Barbour, Adrian Lussi
Jul 6, 2014·Monographs in Oral Science·R Peter ShellisAdrian Lussi
Jul 6, 2014·Monographs in Oral Science·Anderson T Hara, Domenick T Zero
Mar 15, 2015·Caries Research·Jenny Bogstad SøvikAida Mulic
Sep 22, 2018·Archives of Oral Biology·Amela TulekAmer Sehic

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved