Dental management of patients with X-linked hypophosphatemia

Restorative Dentistry & Endodontics
Bin-Na LeeWon-Mann Oh

Abstract

X-linked hypophosphatemia (XLH) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine, and an associated decrease in serum calcium and potassium phosphate. Its dental features include spontaneous dental abscesses that occur in the absence of trauma or dental caries. The aim of this case report was to describe the dental problems of XLH patients and to evaluate limitations in their treatment. A 14 year old male and a 38 year old female with XLH were referred to the Department of Conservative Dentistry for endodontic treatment. The dental findings were periapical abscesses without obvious trauma or caries. Conservative endodontic treatment was performed in teeth with pulp necrosis and abscess. In case 1, the treated teeth showed improvements in bone healing, without clinical symptoms. However, in case 2, the implants and the treated tooth showed hypermobility, and the final restoration was therefore postponed. Early diagnosis, periodic examinations, and communication with the patient's pediatrician are important in the dental management of patients with XLH.

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Citations

Aug 16, 2019·Alimentary Pharmacology & Therapeutics·Trond Espen Detlie, Jørgen Jahnsen
Apr 23, 2019·International Journal of Implant Dentistry·Martin James, Reza Vahid Roudsari
Feb 21, 2018·Journal of Inherited Metabolic Disease·Douglas ChesherElaine Murphy
Nov 19, 2020·Journal of the Endocrine Society·Kathryn DahirJill H Simmons
Apr 1, 2019·Metabolism: Clinical and Experimental·Anya RothenbuhlerAgnes Linglart
Jun 9, 2021·Joint, Bone, Spine : Revue Du Rhumatisme·Justine BacchettaAgnès Linglart
Aug 20, 2021·Journal of Orthodontics·Clara GibsonRobert Evans

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