PMID: 9541227Apr 16, 1998Paper

Dentin matrix proteins

European Journal of Oral Sciences
W T Butler

Abstract

Dentinogenesis consists of highly controlled events occurring a short distance from the periphery of odontoblasts: it involves formation of extracellular collagen fibrils that act as an undergirding for deposition of plate-like carbonate apatite crystals. Odontoblasts also form a set of matrix proteins that are probably secreted at the mineralization front. Although most of these proteins are similar to those of bone, and differ from soft tissue proteins, dentin contains two unique proteins. Dentin phosphoprotein (DPP) is rich in aspartic acid (D) and phosphoserine (S*) and binds large amounts of calcium. DPP contains repeating sequences of DS*S* and S*D in discrete areas of the protein. DS*S* repeats form ridges of phosphates and carboxyllates while the S*D sequences give rise to ridges with phosphates and carboxyllates on opposing sides of the peptide chain. These structures undoubtedly have functional significance since DPP is involved in promotion of mineral initiation and in control of mineral size and shape. Dentin sialoprotein (DSP), found only in dentin, is a 53 kDa glycoprotein rich in aspartic acid, serine, glutamic acid and glycine. DSP is made by odontoblasts and also by pre-ameloblasts, but not by osteoblasts or ot...Continue Reading

Citations

May 16, 2013·Journal of Molecular Histology·Han-Wool ChoungJoo-Cheol Park
May 11, 2012·Biomedical Research·Angela Quispe-SalcedoHayato Ohshima
Dec 28, 2002·Archives of Histology and Cytology·Eiko Watanabe, Yoshiro Takano
Apr 7, 2010·Connective Tissue Research·Monica PrasadChunlin Qin
Jan 19, 2016·Matrix Biology : Journal of the International Society for Matrix Biology·Kostas VerdelisElia Beniash
Mar 30, 2013·Orthodontic Waves : Official Journal of the Japanese Orthodontic Society·Keigo Yoshizaki, Yoshihiko Yamada
Apr 24, 2012·Journal of Dentistry·Izabela Maciejewska, Ewa Chomik
Apr 21, 2012·Journal of Endodontics·Sandra Helena Penha Oliveira, Vanessa Aparecida Carvalho Santos
Jan 19, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Satin SalehiJack Ferracane
Nov 22, 2011·Journal of Endodontics·Avina ParanjpeJames D Johnson
Oct 18, 2011·Journal of Endodontics·Sandra H P Oliveira, Vanessa A C Santos
Apr 27, 2010·Journal of Endodontics·Sueli Patricia Harumi MiyagiMárcia Martins Marques
May 24, 2008·Journal of Endodontics·Yoshiyuki YasudaTakashi Saito
Apr 26, 2008·Journal of Endodontics·Yoshiyuki YasudaTakashi Saito
May 30, 2003·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Henry O Trowbridge
Sep 11, 2012·Journal of Biomedical Materials Research. Part a·Young Suk ChoiYoon Jeong Park
Oct 16, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Pekka NieminenSatu Alaluusua
May 27, 2010·International Endodontic Journal·Y WuX-D Zhou
Jan 10, 2012·Journal of Cellular Biochemistry·Hyun-Jung OhJoo-Cheol Park
Jun 27, 2009·Journal of Biomedical Materials Research. Part a·Xuechao YangJohn A Jansen
Feb 4, 2010·European Journal of Oral Sciences·Miyuki KidaTadashi Ariga
Nov 10, 2004·Matrix Biology : Journal of the International Society for Matrix Biology·Otto BabaWilliam T Butler
Aug 30, 2005·Archives of Oral Biology·Izabela MaciejewskaZdzisław Bereznowski
Nov 16, 2004·Biochemical and Biophysical Research Communications·Kazuhisa NakaoTakashi Tsuji
Nov 28, 2001·Journal of Structural Biology·S HabelitzM Balooch
Nov 23, 2011·BMC Evolutionary Biology·João Paulo MachadoAgostinho Antunes
Sep 27, 2016·Journal of Oral Science·Deniz TorunFerit Avcu
Jul 5, 2002·Journal of Dental Research·C QinW T Butler
May 11, 2002·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·A J Smith, H Lesot

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