Dentine hypersensitivity: a randomised, double-blind placebo-controlled study of the efficacy of a fluoride-sensitive teeth mouthrinse

Journal of Clinical Periodontology
R YatesM Addy

Abstract

Potassium and fluoride salts have been used in the treatment of dentine hypersensitivity (DH). The primary aim of this study was to compare a fluoride-containing mouthrinse product with a placebo rinse for the treatment of DH. A secondary aim was to compare effects on plaque index (PI) and gingivitis index (GI). The study was a double-blind, randomised, two-treatment parallel design involving 91 subjects with DH. At screening, an air evaporative stimulus (AES) was used for selection. Approximately 4 weeks later, at the baseline visit, DH was recorded, using a response-based visual analogue scale (VAS) from upper and lower incisors, canines, premolars and first molars in response to AES and from two to six teeth in response to a cold water stimulus (CWS). PI and GI were also recorded. Subjects were then allocated the test or placebo rinse. On days 28 and 56, VAS scores were again recorded for AES and CWS, with PI and GI recorded at day 56. Both groups improved symptoms to day 28 and again to day 56. The majority of the data favoured the test rinse as more effective but there was no clear evidence for a statistically significant difference between test and placebo. PI at lingual sites approached significance for the test rinse. T...Continue Reading

Associated Clinical Trials

References

Jul 1, 1978·Journal of Periodontal Research·A J Rugg-Gunn, I D Macgregor
May 1, 1979·Journal of Periodontal Research·I D Macgregor, A J Rugg-Gunn
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Citations

Aug 28, 2010·The International Journal of Clinical and Experimental Hypnosis·Stephan EitnerBiljana Sokol
Aug 18, 2012·Journal of Periodontology·Dhelfeson Willya Douglas de OliveiraPatricia Furtado Gonçalves
Jul 27, 2010·Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research·K V V PrasadS B Javali
Jan 8, 2011·Journal of Clinical Periodontology·Hasan Güney YilmazBinnaz Leblebicioglu
Sep 25, 2012·Journal of Dentistry·Kenneth Markowitz
Nov 5, 2013·Acta Odontologica Scandinavica·Rafael Guerra LundFlávio Fernando Demarco
Feb 6, 2008·The Review of Scientific Instruments·David Megias-AlguacilDominik A Ettlin
Nov 7, 2009·Brazilian Oral Research·Ana Cecilia Corrêa AranhaGiselle Maria Marchi
Oct 27, 2009·Brazilian Oral Research·Cassiano Kuchenbecker RösingJuliano Cavagni
Mar 6, 2018·Periodontology 2000·Ilham MounssifGiovanni Zucchelli
Mar 31, 2017·The Open Dentistry Journal·Karlsson Lena, Kjaeldgaard Marianne
May 15, 2020·Dental Materials Journal·Gangjae KimYooseok Shin
Jan 1, 2015·International Scholarly Research Notices·Steven J NaoumAyman Ellakwa
Jul 22, 2016·Journal of Esthetic and Restorative Dentistry : Official Publication of the American Academy of Esthetic Dentistry ... [et Al.]·Haluk Baris KaraPelin Inan Kurugol

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