Apr 23, 1999

Dentocraniofacial morphology in parents of children with cleft lip and/or palate

The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
A SuzukiC Matsuura

Abstract

The purpose of this study was to compare the dentocraniofacial morphology of parents of children with cleft lip and/or palate (CL/P) with that of parents of children without CL/P and to use the results for genetic counseling. Twenty-five fathers and 40 mothers of Japanese children with CL/P, who also had relatives with CL/P within three generations (experimental group), and 413 pairs of parents of children without CL/P (control) were used in this study. To test the accuracy of the discriminant function, 165 subjects were added to this study (test group). Sixty-five dental casts were measured by digital sliding calipers, and 1056 frontal and 1056 lateral cephalograms were traced, digitized, and analyzed using analysis of variance (ANOVA) and discriminant analysis. Mesiodistal tooth diameters in parents of children with CL/P did not show any differences from those in parents of children without CL/P. The parents in the experimental group showed a distinct craniofacial morphology: wider interorbital width (IO-IO'), intercoronoid process distance (Cp-Cp'), and nasal cavity width (NC-NC') and larger anterior cranial base length (S-N) and cranial base length (N-Ba). For genetic counseling, a discriminant function was obtained using f...Continue Reading

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Mentioned in this Paper

Neuro-Oncological Ventral Antigen 2
Family Health Status
Nasal Cavity
Bone Structure of Face
Science of Morphology
Cleft Palate, Isolated
Properdin Deficiency, X-LINKED
Entire Nasal Cavity
Craniometry
Step-parent

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