PMID: 11320620Apr 26, 2001Paper

Dependence of "amplitude modulation following response" on attention

HNO
J PetheH von Specht

Abstract

Amplitude modulation following responses (AMFR) allows good estimation of the hearing threshold due to the very narrow band excitation of the cochlea. Audiological use of AMFR requires knowledge of the relationship of these responses to the state of vigilance. The few studies published compared only qualitatively the amplitude of AMFR recorded in awake subjects to that recorded in sleeping subjects. A quantitative determination of the level of vigilance on the basis of recorded physiological parameters has not yet been carried out. In the present study, the relationship between the amplitude of AMFR and the level of vigilance was investigated quantitatively. In eight adults with normal hearing, the relationship between the AMFR amplitude and EEG amplitude in the delta- and theta-band was determined. The amplitude in both frequency bands was used to indicate the state of vigilance. The subjects were studied during natural and drug-induced sleep. A 1-kHz carrier tone with a sinusoidally modulated amplitude of 40 Hz or 80 Hz was used as stimulus. At 40-Hz modulation frequency, the AMFR amplitude correlates with the EEG amplitude both in natural and drug-induced sleep. An increase in EEG activity is paralleled by a significant redu...Continue Reading

Citations

Aug 26, 2009·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Stefan GräbelHeidi Olze
Sep 25, 2010·PloS One·Elodie BrieferThierry Aubin

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