Dependence of yield strain of human trabecular bone on anatomic site

Journal of Biomechanics
E F Morgan, T M Keaveny

Abstract

Understanding the dependence of human trabecular bone strength behavior on anatomic site provides insight into structure-function relationships and is essential to the increased success of site-specific finite element models of whole bones. To investigate the hypothesis that the yield strains of human trabecular bone depend on anatomic site, the uniaxial tensile and compressive yield properties were compared for cylindrical specimens from the vertebra (n=61), proximal tibia (n=31), femoral greater trochanter (n=23), and femoral neck (n=27) taken from 61 donors (67+/-15years). Test protocols were used that minimized end artifacts and loaded specimens along the main trabecular orientation. Yield strains by site (mean+/-S.D.) ranged from 0.70+/-0.05% for the trochanter to 0.85+/-0.10% for the femoral neck in compression, from 0.61+/-0.05% for the trochanter to 0.70+/-0.05% for the vertebra in tension, and were always higher in compression than tension (p<0.001). The compressive yield strain was higher for the femoral neck than for all other sites (p<0.001), as was the tensile yield strain for the vertebra (p<0.007). Analysis of covariance, with apparent density as the covariate, indicated that inter-site differences existed in yie...Continue Reading

References

Nov 1, 1991·Journal of Biomechanical Engineering·J C LotzW C Hayes
Sep 1, 1991·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·M J CiarelliM B Brown
Aug 1, 1989·Journal of Biomechanical Engineering·C H Turner
Jan 1, 1970·Calcified Tissue Research·J GalanteR D Ray
Jun 1, 1980·Acta Orthopaedica Scandinavica·T D Brown, A B Ferguson
Sep 1, 1994·Journal of Biomechanics·T M KeavenyW C Hayes
Sep 1, 1994·Journal of Biomechanics·T S Keller
Jan 1, 1997·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·T M KeavenyA Lou
Jul 22, 1998·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·M J SilvaW C Hayes
Oct 31, 1998·Journal of Biomechanics·D L Kopperdahl, T M Keaveny
Jan 23, 1999·Topics in Magnetic Resonance Imaging : TMRI·D W Goodwin, J F Dunn
Jul 21, 1999·Journal of Biomechanical Engineering·P K ZyssetS J Hollister
Aug 25, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·W C ChangT M Keaveny
Aug 28, 1999·Journal of Biomechanical Engineering·C M Fenech, T M Keaveny
Mar 30, 2001·Journal of Biomechanical Engineering·E F MorganT M Keaveny
Feb 25, 2003·Journal of Biomechanical Engineering·Glen L NieburTony M Keaveny

❮ Previous
Next ❯

Citations

Nov 8, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B SrinivasanS Khosla
Jun 19, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A I Hussein, E F Morgan
Jul 20, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M E DanielsonJ A Cauley
Jun 9, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Stephen J FergusonAnne Polikeit
Jan 20, 2007·Biomechanics and Modeling in Mechanobiology·Maiko MatsuuraPhilippe K Zysset
May 24, 2007·Biomechanics and Modeling in Mechanobiology·D A DickersonE A Nauman
Mar 22, 2008·Biomechanics and Modeling in Mechanobiology·Sébastien Baïotto, Mustapha Zidi
Apr 25, 2012·Biomechanics and Modeling in Mechanobiology·Noel M HarrisonPeter E McHugh
Sep 18, 2012·Biomechanics and Modeling in Mechanobiology·Nicola KellyJ Patrick McGarry
Dec 16, 2006·Annals of Biomedical Engineering·P McDonnellD O'Mahoney
Jun 26, 2013·Annals of Biomedical Engineering·Ji Yong BaeInsu Jeon
Nov 2, 2011·Journal of Materials Science. Materials in Medicine·Matthew P PrygoskiAntony J Lozier
Mar 13, 2010·Medical & Biological Engineering & Computing·Mohammed Rafiq Abdul KadirAndreas Ochsner
Jul 28, 2004·Journal of Biomechanics·Elise F MorganTony M Keaveny
Jan 11, 2002·Journal of Biomechanics·Michael J JaasmaTony M Keaveny
May 22, 2003·Journal of Biomechanics·Elise F MorganTony M Keaveny
Nov 15, 2003·Journal of Biomechanics·Xiangyi LiuGlen L Niebur
Jan 7, 2004·Journal of Biomechanics·Sean M HaddockTony M Keaveny
Dec 16, 2003·Journal of Biomechanics·Harun H BayraktarTony M Keaveny
Jan 10, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·O C Yeh, T M Keaveny
Aug 10, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·David L KopperdahlTony M Keaveny
Sep 30, 2009·Computer Methods in Biomechanics and Biomedical Engineering·Bidyut PalAndrew M R New
Feb 22, 2011·Computer Methods in Biomechanics and Biomedical Engineering·Loes C DerikxEsther Tanck
Dec 14, 2011·Computer Methods in Biomechanics and Biomedical Engineering·Ibrahim ErdemMarjolein C H van der Meulen
Jan 27, 2012·Journal of the Royal Society, Interface·Elham HamedTadeusz Liszka
Oct 31, 2002·Journal of Biomechanical Engineering·A M MakiyamaL J Gibson
Feb 25, 2003·Journal of Biomechanical Engineering·Glen L NieburTony M Keaveny
Jun 3, 2004·Journal of Biomechanical Engineering·Xiang WangGlen L Niebur
Sep 3, 2004·Journal of Biomechanical Engineering·T L A MooreL J Gibson
Mar 31, 2005·Journal of Biomechanical Engineering·Harun H BayraktarTony M Keaveny
Jul 4, 2006·Journal of Biomechanical Engineering·Todd L Bredbenner, Dwight T Davy
Sep 26, 2006·Journal of Biomechanical Engineering·Jenni M BuckleyTony M Keaveny
Jan 18, 2007·Journal of Biomechanical Engineering·A Perillo-Marcone, M Taylor
Mar 12, 2009·Journal of Biomechanical Engineering·Edward T DavisEmil H Schemitsch
Dec 15, 2010·Journal of Biomechanical Engineering·Mathieu CharleboisPhilippe K Zysset
Aug 10, 2011·Journal of Biomechanical Engineering·Ginu U Unnikrishnan, Elise F Morgan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Biomechanics
David L Kopperdahl, T M Keaveny
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
T M KeavenyA Lou
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
W C ChangT M Keaveny
© 2021 Meta ULC. All rights reserved