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Dependence on dose of the acute effects of ethanol on liver metabolism in vivo

The Journal of Clinical Investigation

Dec 1, 1975

Robert W Guynn, J R Pieklik

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Abstract

The dose dependence of the acute effects of ethanol upon liver intermediary metabolism in vivo has been demonstrated in rats. Ethanol was given i.p. in doses of 0.69, 1.7, and 3.0 g/kg in equal volumes (20 ml/kg). The liver was freeze-clamped 120 min after injection, and multiple metabo...read more

Mentioned in this Paper

Cytoplasmic
Phosphorylation
Intermediary Metabolism
Oxidation-Reduction
NADP
NADH
Dose-Response Relationship, Drug
Generation of Precursor Metabolites and Energy
Ethanol Measurement
Protein Phosphorylation
Paper Details
References
    • References15
    • Citations25
    • References15
    • Citations25
  • Dependence on dose of the acute effects of ethanol on liver metabolism in vivo

    The Journal of Clinical Investigation

    Dec 1, 1975

    Robert W Guynn, J R Pieklik

    PMID: 422

    DOI: 10.1172/jci108222

    Abstract

    The dose dependence of the acute effects of ethanol upon liver intermediary metabolism in vivo has been demonstrated in rats. Ethanol was given i.p. in doses of 0.69, 1.7, and 3.0 g/kg in equal volumes (20 ml/kg). The liver was freeze-clamped 120 min after injection, and multiple metabo...read more

    Mentioned in this Paper

    Cytoplasmic
    Phosphorylation
    Intermediary Metabolism
    Oxidation-Reduction
    NADP

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    Paper Details
    References
    • References15
    • Citations25
    • References15
    • Citations25
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