Depletion of antral gastrin after food in rats

American Journal of Surgery
D D ReederJ C Thompson

Abstract

The results of these studies indicate that in fasting rats, there is an abrupt and prolonged rise in circulating gastrin after feeding. This increase in serum gastrin is accompanied by an early (five minutes) diminution in antral gastrin which is followed by slightly higher and more variable antral gastrin values. These findings suggest that feeding triggers the release of gastrin with early depletion of antral gastrin and that, subsequently, gastrin syhthesis and release interact cyclically to maintain antral and serum concentrations of gastrin. Antral, fundic, and duodenal gastrin values in rats are similar to those reported in dogs and cats. The jejunum of the rat contains little, if any, gastrin.

References

Sep 1, 1973·Annals of Surgery·D D ReederJ C Thompson
Feb 1, 1972·American Journal of Surgery·B M JacksonJ C Thompson

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Citations

Nov 9, 1978·Cell and Tissue Research·N S TrackW Creutzfeldt
Nov 14, 1996·Regulatory Peptides·G GomezG H Greeley
Jan 1, 1989·American Journal of Primatology·Andrew C ScalletPhillip L Rayford
Jan 1, 1977·Acta Pathologica Et Microbiologica Scandinavica. Section A, Pathology·T NormannK M Gautvik
Sep 11, 1996·The American Journal of Physiology·G GomezG H Greeley
Dec 1, 1993·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·M AmiP L Rayford

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