Depression and Anxiety Among Patients on Chronic Opioid Therapy

Health Services Research and Managerial Epidemiology
Muhamad Y ElrashidiJon O Ebbert

Abstract

Chronic noncancer pain (CNCP) and chronic opioid therapy (COT) commonly coexist with comorbid depression and anxiety. We investigated the prevalence of depression and anxiety and their correlates at the time of controlled substance agreement (CSA) enrollment among patients with CNCP and a history of depression or anxiety on COT. Retrospective analysis of 1066 patients in a Midwest primary care practice enrolled in CSAs for COT between May 9, 2013, and August 15, 2016. Patients with self-reported symptoms or a clinical history of depression or anxiety were screened at CSA enrollment using the Patient Health Questionnaire-9 item scale and the Generalized Anxiety Disorder-7 item scale. The percentage of patients screening positive for depression and anxiety at CSA enrollment was 15.4% and 14.4%, respectively. Patients screening positive for depression or anxiety were more likely to be younger, unmarried, unemployed, and live alone compared to patients not screening positive. Patients screening positive for depression or anxiety were more likely to smoke cigarettes and report concern from friends or relatives regarding alcohol consumption. Compared to patients screening negative, patients screening positive for depression had highe...Continue Reading

References

Aug 1, 1992·Pain·Michael Von KorffSamuel F Dworkin
Jun 1, 1992·Journal of Clinical Epidemiology·R A DeyoM A Ciol
Dec 1, 1991·Archives of General Psychiatry·N BreslauP Andreski
Sep 5, 2001·Journal of Pain and Symptom Management·N J AdamsE A Stauffacher
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Apr 4, 2002·Journal of General Internal Medicine·M Carrington ReidPatrick G O'Connor
Nov 12, 2003·Archives of Internal Medicine·Matthew J BairKurt Kroenke
Jan 13, 2004·Pain·Annmarie CanoHeather Foran
Mar 19, 2005·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Douglas L GourlayAbdulaziz Almahrezi
May 24, 2006·Archives of Internal Medicine·Robert L SpitzerBernd Löwe
Mar 21, 2007·Journal of General Internal Medicine·Jaishree HariharanJoan M Neuner
Oct 13, 2007·Depression and Anxiety·Adrienne J Means-ChristensenMurray B Stein
Jun 25, 2008·The Clinical Journal of Pain·Dennis C TurkRobert J Gatchel
Jun 25, 2008·The Clinical Journal of Pain·Michael Von KorffConstance Weisner
Feb 4, 2009·The Journal of Pain : Official Journal of the American Pain Society·Roger ChouUNKNOWN American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
Apr 27, 2010·The Journal of Pain : Official Journal of the American Pain Society·Jennifer Barsky ReeseMark A Lumley
Jul 16, 2010·The Journal of Pain : Official Journal of the American Pain Society·Declan T BarryDavid A Fiellin
Jan 1, 2013·Mayo Clinic Proceedings·Jennifer L St SauverWalter A Rocca
Apr 27, 2013·The American Journal on Addictions·Daniel F GrosSudie E Back
Jun 2, 2015·The Journal of Pain : Official Journal of the American Pain Society·Richard L Nahin
Jan 13, 2016·Annals of Family Medicine·Jeffrey F ScherrerPatrick J Lustman
Feb 18, 2016·The Journal of Pain : Official Journal of the American Pain Society·Jeffrey F ScherrerPatrick J Lustman
May 21, 2016·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Meg FluhartyMarcus R Munafò

❮ Previous
Next ❯

Citations

Dec 31, 2019·Clinical and Experimental Pharmacology & Physiology·Thomas AntonySabah H El-Ghaiesh

❮ Previous
Next ❯

Software Mentioned

Statistical Analysis

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Pharmaceutical Policy and Practice
Lindsey M PhilpotJon O Ebbert
Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse
Erik W GundersonFrances R Levin
American Family Physician
Dean A Seehusen
British Journal of Anaesthesia
B J Collett
© 2022 Meta ULC. All rights reserved