Depression and cardiovascular disease: selected findings, controversies, and clinical implications from 2009.

Cleveland Clinic Journal of Medicine
Karina W Davidson, Maya Rom Korin

Abstract

We systematically searched published empirical research on depression and cardiovascular disease (CVD) and found 494 unique articles published in 2009. Several particularly notable and provocative findings and controversies emerged from this survey of the 2009 literature. First, multiple large observational studies found that antidepressant use was associated with increased risk of incident stroke, CVD, or sudden cardiac death. Second, four randomized controlled trials on depression interventions in CVD patients reported important efficacy results that should guide future trials. Finally, the vigorous debate on whether patients with CVD should be routinely screened (and subsequently treated) for depression continued in 2009 even as some observed that routine screening for CVD in depressed patients is more evidence-based and appropriate. This article reviews these selected provocative findings and controversies from our search and explores their clinical implications.

References

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Aug 10, 2002·JAMA : the Journal of the American Medical Association·Alexander H GlassmanUNKNOWN Sertraline Antidepressant Heart Attack Randomized Trial (SADHEART) Group
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Aug 29, 2009·Journal of the American College of Cardiology·Mary A Whooley
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Nov 18, 2009·JAMA : the Journal of the American Medical Association·Bruce L RollmanCharles F Reynolds

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Citations

Sep 2, 2011·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·R A M Erdman, S S Pedersen
Jun 15, 2011·Journal of Psychosomatic Research·Emmanuelle CorrubleDidier Samuel
Nov 26, 2015·International Journal of Cardiology·Corline BrouwersSusanne S Pedersen
Nov 15, 2018·Hormone Molecular Biology and Clinical Investigation·Kai G Kahl
Jun 14, 2014·Journal of Immigrant and Minority Health·Tam Truong DonnellySarah Omar
Jan 4, 2013·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Anthony W McGuireLynn V Doering
Aug 19, 2018·Journal of Immigrant and Minority Health·Tam Truong DonnellyRajvir Singh
Mar 1, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Maria T BekendamIlse A C Vermeltfoort

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