PMID: 9527152Apr 4, 1998Paper

Depression and its relation to lesion location after stroke

Journal of Neurology, Neurosurgery, and Psychiatry
S MacHaleM Dennis

Abstract

The study of discrete organic cerebral lesions resulting in clearly definable psychiatric disorders may provide an understanding of the underlying pathophysiological basis of these disorders. However, the relation between lesion location and psychiatric illness after stroke remains unclear. Fifty five patients referred to hospital were identified who had a single lesion on CT which was consistent with their neurological presentation and who did not have evidence of a persistent affective disorder at the time of the stroke. Six months after stroke standardised psychiatric assessment disclosed that 26% of the patients met DSM-IV criteria for an anxiety or depressive disorder, with depression the most common diagnosis (20%). Pathological emotionalism was diagnosed in 18% of patients, particularly those who were depressed (p<0.0001). Depression was significantly associated with larger lesions involving the right cerebral hemisphere (p=0.01). The importance of depression as a consequence of stroke has been clarified by the studies in this area. However, wide confidence intervals support the possibility that significant results may be due to chance. A systematic review of these studies is now needed if a consensus is to be reached.

Citations

Jul 29, 2004·Current Treatment Options in Neurology·James A. BourgeoisMark E. Servis
Mar 17, 2004·Journal of Affective Disorders·Alan J ThomasJohn T O'Brien
Oct 17, 2008·Neuropsychological Rehabilitation·Catherine HaslamW Huw Williams
Mar 17, 2007·Psychology, Health & Medicine·Janet W H SitLeonard S W Li
Jan 18, 2002·Current Opinion in Neurology·Antonio CarotaJulien Bogousslavsky
Dec 22, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·M DennisC Warlow
Apr 20, 2014·TheScientificWorldJournal·Chao FengXue-Yuan Liu
Dec 3, 2014·Archives of Psychiatric Nursing·Ning SunMei-Ling Sun
Oct 12, 2004·The Kaohsiung Journal of Medical Sciences·Lifa YuShenq-Horng Yu
Nov 28, 2008·Clinical Neurology and Neurosurgery·Yangkun ChenWai Kwong Tang
Sep 6, 2008·Revue neurologique·G L LenziI Maestrini
Feb 17, 2006·The British Journal of Clinical Psychology·Shirley A Thomas, Nadina B Lincoln
Sep 15, 2011·International Journal of Geriatric Psychiatry·Jae-Min KimJin-Sang Yoon
Mar 31, 2011·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Seiji HamaKaoru Kurisu
Sep 17, 1999·Archives of Physical Medicine and Rehabilitation·S PaolucciS Lubich
Oct 14, 2014·Journal of Neurology·Na WeiHuijuan Jin
Mar 11, 2004·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·David A BennettSteven E Arnold
Apr 9, 2008·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·R M W OliveiraJ F W Deakin
Jan 19, 2017·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Ozgur Z KaraahmetAytul Cakci
Apr 8, 2017·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Kadir KarakusLevent Sevincok
May 24, 2000·International Journal of Geriatric Psychiatry·R Rao
Feb 14, 2004·Stroke; a Journal of Cerebral Circulation·Sanjit K BhogalMark Speechley
Jan 4, 2003·Stroke; a Journal of Cerebral Circulation·Anu BergMarkku Kaste
Dec 20, 2007·Expert Review of Neurotherapeutics·Jorge Moncayo Gaete, Julien Bogousslavsky
Feb 2, 2002·The British Journal of Psychiatry : the Journal of Mental Science·Robert C Baldwin, John O'Brien
Jan 30, 2014·Psychiatry Investigation·Dong-Ho ChoiJin-Sang Yoon
Aug 24, 2017·Neuropsychology Review·Elles DouvenPauline Aalten
Oct 7, 2017·Frontiers in Neurology·Alina Nickel, Götz Thomalla
Mar 9, 2021·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Eunhee ParkTae-Du Jung
Jan 17, 2020·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Lauren E FournierAnjail Z Sharrief
Apr 13, 2021·Frontiers in Neurology·Fei LiuYong-Jun Wang

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