Depression and metabolic syndrome in the older population: A review of evidence

Journal of Affective Disorders
Nikolena RepousiStefanos Tyrovolas

Abstract

Metabolic syndrome (MetS) has been shown to be associated with depression in older adults but the results are mixed. We summarized and evaluated the association between depression and MetS in people aged 60 years or over. Relevant published studies from January 1997 to July 2017 were identified by searching two electronic databases: PubMed/Medline and EMBASE. Observational studies were considered. Twelve studies were included in the systematic review. Depression seemed to be related with MetS in the majority of the studies (10/12 = 83.3%). As far as the longitudinal studies are concerned, the onset of depression was related to MetS in 2 out of 3 studies (66.6%), while a relation between chronicity of depression and MetS was reported (1 study). Regarding cross-sectional studies, 7 out of 9 (77.7%) concluded that there was a positive association between depression and MetS. Mixed evidence was found among studies concerning the association between depression and the individual components of MetS. Four out of ten studies (40%) reported that depression was significantly associated with the waist circumference, a component of MetS. There was a high degree of heterogeneity between studies regarding their design. Only studies written i...Continue Reading

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Citations

May 13, 2020·Journal of Physical Activity & Health·Allysiê Priscilla de Souza CavinaFranciele Marques Vanderlei
May 14, 2020·Journal of the American Geriatrics Society·Bruno AgustiniUNKNOWN ASPREE Investigator Group
Sep 13, 2019·The Clinical Journal of Pain·Takaaki IkedaKen Osaka
Dec 9, 2020·Journal of Affective Disorders·Weibin HuangJing Zhang
Oct 13, 2020·Mechanisms of Ageing and Development·Federico TrioloSerhiy Dekhtyar
Jan 14, 2020·Journal of the American Medical Directors Association·Shan-Shan YaoBeibei Xu
May 6, 2021·Journal of Sports Science & Medicine·Paulina MorgaJoanna Szczepańska-Gieracha
Jun 3, 2021·International Journal of Environmental Research and Public Health·Azad R BhuiyanFrank Smart
Jul 7, 2021·Revista de psiquiatrí́a y salud mental·Alejandro de la Torre-Luque, Jose Luis Ayuso-Mateos
Aug 3, 2021·Psychological Medicine·Shimrit DachesMaria Kovacs

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