Depression, antidepressants and low hemoglobin level in the Paris Prospective Study III: A cross-sectional analysis.

Preventive Medicine
Hélène VulserJean-Philippe Empana

Abstract

Anemia is known to be associated with depression both in community and clinical populations. However, it is still unknown if this association depends or not on antidepressant intake. We investigated the respective association of depression and antidepressant intake with low hemoglobin level in a large community-based cohort. In 8640 volunteers aged 50 to 75 recruited between June 2008 and June 2012 in Paris (France), we assessed hemoglobin levels (g/dl), depressive symptoms and antidepressant intake. We examined the association of both depression and antidepressant intake with hemoglobin level, adjusting for numerous socio-demographic and health variables. We also assessed the association with specific antidepressant classes. Depression and antidepressant intake were independently associated with lower hemoglobin level (β = -0.074; p = .05 and β = -0.100; p = .02 respectively in the fully-adjusted model). Regarding antidepressant classes, selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) intake were associated with lower hemoglobin level (β = -0.11; p = .01). To conclude, both depression and antidepressant intake were associated with lower hemoglobin level. In particular, a...Continue Reading

References

Oct 8, 1999·Journal of the National Cancer Institute·J E Groopman, L M Itri
Mar 28, 2001·Annals of the New York Academy of Sciences·G J Maestroni
Jul 12, 2001·Annals of Hematology·C MitracheA Tichelli
Feb 14, 2004·European Journal of Haematology·Guenter WeissDietmar Fuchs
Nov 24, 2004·Archives of Internal Medicine·Welmoed E E MeijerAntoine C G Egberts
Sep 27, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Graziano OnderLuigi Ferrucci
Mar 16, 2007·Brain, Behavior, and Immunity·Michael R Irwin, Andrew H Miller
Aug 7, 2008·American Journal of Epidemiology·Stephen R Cole, Miguel A Hernán
Jun 2, 2009·Journal of the American Geriatrics Society·Tze-Pin NgKeng-Bee Yap
Jul 29, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Wendy P J den ElzenJacobijn Gussekloo
Dec 31, 2010·The Journal of Clinical Psychiatry·Chittaranjan AndradeKoregala S Nagesh
Jul 27, 2011·Proceedings of the National Academy of Sciences of the United States of America·Pascal AmireaultFrancine Côté
Sep 29, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Christopher LabosElham Rahme
Oct 4, 2011·European Journal of Epidemiology·Jean-Philippe EmpanaUNKNOWN PPS3 Study Group
Oct 25, 2011·Psychosomatic Medicine·Cédric LemogneNicolas Danchin
Sep 12, 2013·Circulation. Cardiovascular Quality and Outcomes·M Alan BrookhartTil Stürmer
Sep 17, 2013·Psycho-oncology·Shawna L KraftJolene R Bostwick
Dec 21, 2013·PloS One·Pascal AmireaultFrancine Côté
Mar 19, 2014·Journal of Psychosomatic Research·Bianca A Lever-van MilligenBrenda W J H Penninx
Aug 25, 2015·Frontiers in Cellular Neuroscience·Marco CosentinoGeorges J M Maestroni
Oct 19, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·L E GrzeskowiakV L Clifton
May 31, 2016·Acta Psychiatrica Scandinavica·H VulserC Lemogne
Apr 27, 2017·Progress in Neuro-psychopharmacology & Biological Psychiatry·Magdalena WiędłochaAgata Szulc

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.