Depression, anxiety and obsessive-compulsive symptoms and quality of life in children with attention-deficit hyperactivity disorder (ADHD) during three-month methylphenidate treatment

Journal of Psychopharmacology
Kagan GürkanRuna Uslu

Abstract

The current study was designed to investigate the changes that occur in depression, anxiety, obsessive-compulsive symptoms and health-related quality of life during methylphenidate (MPH) treatment in children with attention-deficit hyperactivity disorder (ADHD). Forty-five treatment naive children with ADHD, aged 8-14, were assessed based on self, parent and teacher reports at the baseline and at the end of the first and third month of MPH treatment regarding changes in inattention, hyperactivity, impulsivity, depression, anxiety and obsessive-compulsive symptoms. Changes in the quality of life were also noted. Repeated measures of analysis of variance (ANOVA) tests with Bonferroni corrections were conducted in order to evaluate the data. Symptoms of inattention, hyperactivity and impulsivity were significantly reduced (p < 0.017) following a three-month MPH treatment. There were significant decreases in depression (p = 0.004), trait anxiety (p = 0.000) and checking compulsion symptom scores (p = 0.001). Moreover, parents reported significant improvements in psychosocial (p = 0.001) and total scores (p = 0.009) of quality of life, despite no change in physical health scores (p > 0.05). Children's ratings of quality of life meas...Continue Reading

References

Jan 1, 1977·Behaviour Research and Therapy·R J Hodgson, S Rachman
Mar 1, 1992·Journal of the American Academy of Child and Adolescent Psychiatry·S R Pliszka
Aug 1, 1991·Journal of Clinical Psychopharmacology·R T JoffeA J Levitt
Dec 1, 1987·Journal of Clinical Psychopharmacology·R T Joffe, R P Swinson
Jul 1, 1972·Clinical Pharmacology and Therapeutics·K RickelsH S Wentz
May 1, 1970·Journal of the American Podiatry Association·S R Kaner
Jan 1, 1995·International Journal of Psychiatry in Medicine·F FernandezP Ruiz
Jul 1, 1995·Journal of the American Academy of Child and Adolescent Psychiatry·R TannockR Schachar
Jul 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·G J DuPaulM B McMurray
Aug 1, 1996·Journal of the American Academy of Child and Adolescent Psychiatry·D P Cantwell
Feb 25, 1998·Journal of the American Academy of Child and Adolescent Psychiatry·S Kouris
Aug 13, 1998·Journal of Abnormal Child Psychology·C K ConnersJ N Epstein
Apr 13, 1999·Journal of the American Academy of Child and Adolescent Psychiatry·I R DiamondR J Schachar
Feb 9, 2002·Journal of the American Academy of Child and Adolescent Psychiatry·Laurence L GreenhillUNKNOWN American Academy of Child and Adolescent Psychiatry
Aug 24, 2004·European Child & Adolescent Psychiatry·Christopher GillbergLena Niklasson
Jun 30, 2005·Journal of Psychiatric Practice·Margaret WeissGabrielle Weiss
Jul 19, 2005·Lancet·Joseph Biederman, Stephen V Faraone
May 8, 2007·European Child & Adolescent Psychiatry·L Hakkaart-van RoijenJ K Buitelaar
Mar 21, 2008·Developmental Medicine and Child Neurology·Boudien C T Flapper, Marina M Schoemaker
Jan 24, 2009·European Archives of Psychiatry and Clinical Neuroscience·Michael RöslerWolfgang Retz

❮ Previous
Next ❯

Citations

May 2, 2014·Annales pharmaceutiques françaises·H JavelotB Kabuth
Oct 24, 2012·Journal of Psychiatric Research·Antonio Molina-CarballoAntonio Muñoz-Hoyos
Oct 29, 2014·European Child & Adolescent Psychiatry·Arunima RoyAlbertine J Oldehinkel
Oct 22, 2013·International Journal of Pediatric Otorhinolaryngology·Kemal ÖzcanKübra Durukan
Mar 10, 2017·Expert Opinion on Drug Safety·Annabeth P GroenmanPieter J Hoekstra
Feb 21, 2013·Journal of Attention Disorders·Anthony RostainStephen V Faraone
Feb 10, 2019·Molecular Brain·Rongyi ZhouYuchen Song
Apr 17, 2017·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Sara Loureiro-VieiraJoão Paulo Capela
May 1, 2018·Journal of Attention Disorders·Seda Erbilgin Gün, Ayse Kilincaslan
Mar 7, 2012·Arquivos de neuro-psiquiatria·Elizabeth Zambrano-SánchezAdrián Poblano
Oct 22, 2020·International Clinical Psychopharmacology·Pavel Golubchik, Abraham Weizman
Dec 29, 2020·Epilepsy & Behavior : E&B·Beth A Leeman-MarkowskiKimford J Meador

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Related Papers

The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry
Michael RöslerRichard Ammer
Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)
M Tomás VilaI Pitarch Castellano
© 2022 Meta ULC. All rights reserved