Depression in Older Patients in Residential Care: Significance of Dysphoria and Dimensional Assessment

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Ira R KatzJoel E Streim

Abstract

To investigate the significance of subsyndromal depressive states in geriatric patients, the authors used data from ongoing studies of depression in older patients in residential care to evaluate the clinical correlates of dysphoria. They find that dysphoria is, in general, a persistent state associated with increased medical illness, pain, self-care deficits, and mortality relative to euthymic subjects; thus it is clinically significant. Differences between dysphoria and major depression in the extent of associated disability and mortality, but not in measures of medical illness, pain, or persistence, remain significant after controlling for self-ratings of depression from the Geriatric Depression Scale. This finding suggests that dimensional assessments can account for some of the correlates of depression, but that categorical diagnoses are required for others.

Citations

Oct 23, 2001·Depression and Anxiety·E J LenzeC F Reynolds
Sep 2, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Warren D Taylor, P Murali Doraiswamy
Jun 20, 2018·Clinical Gerontologist·Rebecca ChauTanya E Davison
Apr 11, 2003·Current Psychiatry Reports·Eric J Lenze
Oct 13, 2007·International Journal of Geriatric Psychiatry·George S AlexopoulosPatricia A Arean
Oct 1, 1996·Postgraduate Medicine·S Zisook
Jul 3, 2019·Clinical Gerontologist·Rebecca ChauTanya E Davison
Feb 1, 1996·Journal of the American Geriatrics Society·B W RovnerY Shmuely-Dulitzki
Apr 25, 2007·International Psychogeriatrics·Kuruvilla GeorgeKathleen Moore
Oct 4, 2002·Biological Psychiatry·George S AlexopoulosK Ranga R Krishnan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Andrew GrabovichJeffrey M Lyness
The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Jeffrey M LynessEric D Caine
© 2022 Meta ULC. All rights reserved