Depression Prevalence, Antidepressant Treatment Status, and Association with Sustained HIV Viral Suppression Among Adults Living with HIV in Care in the United States, 2009-2014

AIDS and Behavior
Runa H GokhaleHeather Bradley

Abstract

Previous research indicates a high burden of depression among adults living with HIV and an association between depression and poor HIV clinical outcomes. National estimates of diagnosed depression, depression treatment status, and association with HIV clinical outcomes are lacking. We used 2009-2014 data from the Medical Monitoring Project to estimate diagnosed depression, antidepressant treatment status, and associations with sustained viral suppression (all viral loads in past year < 200 copies/mL). Data were obtained through interview and medical record abstraction and were weighted to account for unequal selection probabilities and non-response. Of adults receiving HIV medical care in the U.S. and prescribed ART, 27% (95% confidence interval [CI] 25-29%) had diagnosed depression during the surveillance period; the majority (65%) were prescribed antidepressants. The percentage with sustained viral suppression was highest among those without depression (72%, CI 71-73%) and lowest among those with untreated depression (66%, CI 64-69%). Compared to those without depression, those with a depression diagnosis were less likely to achieve sustained viral suppression (aPR 0.95, CI 0.93-0.97); this association held for persons with ...Continue Reading

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Citations

Feb 16, 2021·Expert Opinion on Pharmacotherapy·Mina BorranHossein Khalili
Feb 19, 2021·AIDS and Behavior·Mathilda ReganChristopher R Sudfeld
Mar 11, 2021·AIDS Patient Care and STDs·Amanda Blair SpenceSeble Kassaye
May 21, 2021·Current HIV/AIDS Reports·Noelle A MendezSteven A Safren
Jun 6, 2021·Human Brain Mapping·Margarita BronshteynXiong Jiang
Nov 19, 2021·Current HIV/AIDS Reports·Jacqueline HoareNicole Phillips

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