Depression screening in patients with brain tumors: a review

CNS Oncology
Aiste Pranckeviciene, Adomas Bunevicius

Abstract

Brain tumor (BT) is often a devastating disease associated with poor prognosis. Depression is a common complication in BT patients that often remains under-recognized and untreated. Implementation of reliable depression screening algorithms in routine neuro-oncology setting could potentially improve recognition of depression. The Hospital Anxiety and Depression scale-Depression subscale and Patient Health Questionnaire-9 demonstrated adequate psychometric properties for depressive disorder screening in glioma patients. Patients screened positive for depression should be referred for detailed psychiatric assessment prior to initiating anti-depressive treatment. Further methodologically rigorous studies investigating psychometric properties of single-item and multiple-item depression scales are urgently warranted. Studies evaluating anti-depressive treatments' efficacy and clinical value of depression biomarkers are important avenues for future research endeavors in BT patients.

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Citations

Feb 13, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Aiste PranckevicieneAdomas Bunevicius
Feb 8, 2016·Acta neurochirurgica·Adomas Bunevicius, Arimantas Tamasauskas
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Nov 17, 2020·Frontiers in Human Neuroscience·Fabiola SilvaggiSilvia Schiavolin
Mar 5, 2021·Technical Innovations & Patient Support in Radiation Oncology·Ulrica LangegårdKarin Ahlberg

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