Depression symptoms predict heart rate recovery after treadmill stress testing

American Heart Journal
Joel W HughesRichard Josephson

Abstract

Altered autonomic nervous system (ANS) functioning may help to explain the relationship between depression and cardiac mortality. Heart rate (HR) recovery after the cessation of a treadmill stress test assesses ANS functioning and predicts mortality. This study examined the relationship between depression symptoms and HR recovery among patients entering phase II cardiac rehabilitation. Two hundred sixty patients were assessed at the time of their enrollment in cardiac rehabilitation. Patients completed a ramped-protocol treadmill stress test, providing an assessment of exercise capacity and HR recovery at 2 minutes post exercise. Depression symptoms were measured using the Beck Depression Inventory. Other medical information was obtained by chart review. Patients with higher Beck Depression Inventory scores exhibited slower HR recovery after exercise. This remained true after controlling for age, sex, and beta-blocker usage. Controlling for exercise capacity rendered the relationship between depression score and HR recovery non significant, suggesting that exercise capacity may partly account for this relationship. These findings confirm that depression is characterized by dysregulation of the ANS and implicate impaired exercis...Continue Reading

References

Feb 15, 1995·Circulation·N Frasure-SmithM Talajic
Sep 15, 1995·The American Journal of Cardiology·R M CarneyA S Jaffe
Oct 20, 1993·JAMA : the Journal of the American Medical Association·N Frasure-SmithM Talajic
Sep 15, 1996·The American Journal of Cardiology·J C BarefootR B Williams
Feb 19, 1999·Psychosomatic Medicine·N Frasure-SmithM G Bourassa
Oct 28, 1999·The New England Journal of Medicine·C R ColeM S Lauer
Apr 28, 2000·Journal of the Autonomic Nervous System·G L PierpontC C Gornick
Sep 16, 2000·JAMA : the Journal of the American Medical Association·E O NishimeM S Lauer
May 18, 2001·The American Journal of Cardiology·M Y DesaiF Mannting
Oct 24, 2001·Circulation·R M CarneyK E Freedland
Mar 14, 2003·The American Journal of Cardiology·Samuli I NissinenHeikki V Huikuri
Apr 2, 2003·Journal of Cardiopulmonary Rehabilitation·Susan TiukinhoyMichael Hsie
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Jun 9, 2004·Psychosomatic Medicine·Heather S LettMark F Newman
Jun 29, 2004·The American Journal of Cardiology·Gordon L Pierpont, Eric J Voth
Jun 29, 2004·The American Journal of Cardiology·Bernice RuoMary A Whooley
Nov 27, 2004·Psychosomatic Medicine·Jürgen BarthChristoph Herrmann-Lingen
May 13, 2005·The New England Journal of Medicine·Xavier JouvenPierre Ducimetière
Jun 15, 2005·Psychosomatic Medicine·Nancy Frasure-Smith, François Lespérance
Jun 15, 2005·Psychosomatic Medicine·Robert M CarneyRichard C Veith
Jun 15, 2005·Psychosomatic Medicine·Erica C Bruce, Dominique L Musselman
Jun 15, 2005·Psychosomatic Medicine·Willem J Kop, John S Gottdiener
Jun 15, 2005·Psychosomatic Medicine·Kenneth E FreedlandJudith A Skala
Apr 1, 1995·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·R M CarneyA S Jaffe

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Citations

Aug 23, 2008·Journal of Behavioral Medicine·Elizabeth CaseyJames Rosneck
Sep 19, 2012·Cardiovascular Psychiatry and Neurology·Therese A KearyJohn Gunstad
Apr 26, 2011·Journal of Mathematical Psychology·Tom LodewyckxLisa Sheeber
Mar 6, 2016·Journal of Behavioral Medicine·Kristin J HorsleyTavis S Campbell
Aug 3, 2011·Psychophysiology·Jennifer L GordonSimon L Bacon
Sep 26, 2012·Autonomic Neuroscience : Basic & Clinical·Jaana J KarjalainenMikko P Tulppo
Oct 23, 2018·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Chiara A M SpatolaEnrico Molinari
Jul 19, 2016·Journal of Cardiopulmonary Rehabilitation and Prevention·Theodoros PapasavvasDominic Micklewright
Sep 14, 2018·Frontiers in Psychology·Gaelle TanguyMarion Trousselard

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