Depression trajectories, inflammation, and lifestyle factors in adolescence: The TRacking Adolescents' Individual Lives Survey

Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association
Hester E DuivisPeter de Jonge

Abstract

In adults, depression and inflammation are bidirectionally related. This association is less clear in adolescents. Moreover, somatic and cognitive depressive symptoms might be differentially related to inflammation. Lifestyle factors, as in adults, may play an important mediating role in adolescents. For the current study we evaluated trajectories of depressive symptoms in adolescence over a 5-year course and their relation with subsequent high-sensitivity C-reactive protein (hsCRP) levels, and examined lifestyle factors as mediators. Participants of the TRacking Adolescents' Individual Lives' Survey (TRAILS; N = 1166) were followed from 2001 until 2008. Three biennial youth self-report (YSR) assessments of depressive symptoms were taken. Demographics, health, and lifestyle factors and levels of hsCRP were assessed at Wave 3. Latent-class analysis was used to determine trajectories of depression and general linear models to determine the association between depression trajectories and hsCRP. Finally, mediation analysis was performed to test mediation of lifestyle factors. Persistently moderate to high depressive symptoms were associated with higher hsCRP levels. Results were unaltered when we adjusted for demographics and healt...Continue Reading

Citations

Aug 3, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M A C Van SonB L Den Oudsten
Aug 9, 2018·Journal of Youth and Adolescence·Daniel P MoriarityLauren B Alloy
Feb 15, 2019·Clinical and Experimental Immunology·C D MoultonN Powell
Jul 30, 2020·Clinical Psychological Science : a Journal of the Association for Psychological Science·Daniel P MoriarityLauren B Alloy
Jul 26, 2019·Clinical Psychological Science : a Journal of the Association for Psychological Science·Daniel P MoriarityLauren B Alloy
Sep 3, 2020·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·César Agostinis-SobrinhoRute Santos
Mar 10, 2019·Brain, Behavior, and Immunity·Jessica J ChiangAndrew J Fuligni
Jun 25, 2021·Journal of Child and Adolescent Psychopharmacology·Qi LiuVilma Gabbay

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Epidemiology
Seounghee LeeJoohon Sung
Pediatrics International : Official Journal of the Japan Pediatric Society
Ruth SofermanYosef Weisman
Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association
Anne van GilsJudith G M Rosmalen
Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association
Brittney SchirdaRuchika Shaurya Prakash
© 2021 Meta ULC. All rights reserved