Depressive symptoms and 10-year risk for cardiovascular morbidity and mortality

The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry
Hannu KoponenMauno Vanhala

Abstract

Depression is associated with increased physical morbidity and overall mortality. As less is known about how much depression increases the 10-year risk for fatal and nonfatal cardiovascular (CV) events, we evaluated the cross-sectional risk with two well-characterized risk functions measuring CV mortality and total CV event risk. The prevalence of increased depressive symptoms was measured with the Beck Depression Inventory (BDI), and the SCORE and Framingham risk functions were calculated in a middle-aged population-based sample (N=923). For metabolic syndrome (MetS), the modified National Cholesterol Education Program-Adult Treatment Panel III criteria were employed. Depressive symptoms were associated with increased CV mortality and morbidity risk in men: OR for SCORE 2.9; 95%CI 1.4-5.7 and OR for Framingham function 2.2 (95%CI 1.1-4.2). In women, the corresponding figures were 1.4 (95%CI 0.3-6.9) and 1.3 (95%CI 0.7-2.6). The BDI scores showed significant correlations with SCORE (r=0.18 for men, P < 0.001; and r=0.14 for women, P=0.002), and Framingham function (for men r=0.16, P < 0.001; and for women r=0.13, P=0.005). Our results suggest that screening and effective treatment of depression are important in the primary and ...Continue Reading

References

May 29, 1998·Circulation·P W WilsonW B Kannel
Apr 1, 1999·Journal of Clinical Psychology·R A SteerA T Beck
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Nov 27, 2002·Journal of Affective Disorders·Pim Cuijpers, Filip Smit
Jun 6, 2003·European Heart Journal·R M ConroyUNKNOWN SCORE project group
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Nov 14, 2003·European Heart Journal·Ralph A H StewartUNKNOWN Long-Term Intervention With Pravastatin in Ischaemic Disease (LIPID) Study Investigators
Nov 27, 2004·Psychosomatic Medicine·Jürgen BarthChristoph Herrmann-Lingen
Nov 27, 2004·Psychosomatic Medicine·Susan A Everson-RoseRichard P Mero
Dec 1, 2004·Stroke; a Journal of Cerebral Circulation·Brooks B GumpUNKNOWN MRFIT Research Group
Dec 18, 2004·BMJ : British Medical Journal·Markku TimonenSirkka Keinänen-Kiukaanniemi
Aug 9, 2005·American Heart Journal·Amy K FerketichPhilip F Binkley
May 30, 2006·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Marijke A BremmerAartjan T F Beekman
Nov 21, 2007·Journal of the American College of Cardiology·Viola VaccarinoUNKNOWN National Heart, Lung, and Blood Institute
Dec 26, 2007·Psychosomatic Medicine·Viola VaccarinoC Noel Bairey Merz
Feb 1, 2008·The Journal of Clinical Psychiatry·Hannu KoponenMauno Vanhala
Mar 19, 2008·Nursing Research·Srichand JastiEva Goldwater
Mar 29, 2008·Journal of the American College of Cardiology·Joel E Dimsdale
Jul 4, 2008·Biological Psychiatry·Lucile CapuronViola Vaccarino
Aug 13, 2008·Journal of Affective Disorders·Marjolein H KamphuisDaan Kromhout
Nov 20, 2008·Acta Psychiatrica Scandinavica·M VanhalaH Koponen
Jun 25, 2009·Current Opinion in Cardiology·Anne N Thorndike, Nancy A Rigotti
Dec 3, 2009·JAMA : the Journal of the American Medical Association·Ioanna TzoulakiJohn P A Ioannidis

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Citations

May 21, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Päivi E KorhonenHannu Kautiainen
Nov 5, 2014·Nordic Journal of Psychiatry·Hannu KoponenMauno Vanhala
Dec 3, 2014·Primary Care Diabetes·Päivi E KorhonenRisto Kaaja
Mar 7, 2014·Scandinavian Journal of Primary Health Care·Päivi E KorhonenHannu Kautiainen
Jul 13, 2011·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Adrie SeldenrijkBrenda W J H Penninx
May 21, 2011·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Alessandro SerrettiDiana De Ronchi
Feb 11, 2015·Journal of Hypertension·Päivi Elina KorhonenIlkka Kantola
Feb 23, 2012·Journal of Affective Disorders·Jussi SeppäläMauno Vanhala
Aug 27, 2013·Journal of Psychosomatic Research·I-Chia ChienPesus Chou
Dec 25, 2016·Journal of Endocrinological Investigation·A V LemcheE Lemche
Oct 1, 2014·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Päivi E KorhonenPekka Mäntyselkä
Jan 25, 2011·Psychosomatic Medicine·Floriana S LuppinoBrenda W J H Penninx
Jun 18, 2019·Scandinavian Journal of Medicine & Science in Sports·Hanna JantunenJohan G Eriksson
Jun 21, 2017·International Journal of Psychiatry in Medicine·Ehsan Moazen-ZadehArash Rahmani
Jul 4, 2017·Depression and Anxiety·Chad D RethorstMadhukar H Trivedi
Jan 10, 2020·Primary Care Diabetes·Susanna KuneinenPäivi E Korhonen
Jun 8, 2021·Scandinavian Journal of Primary Health Care·Susanna M KuneinenPäivi E Korhonen

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