Depressive symptoms and AIDS-related mortality among a multisite cohort of HIV-positive women

American Journal of Public Health
Judith A CookNancy A Hessol

Abstract

We examined associations between depressive symptoms and AIDS-related mortality after controlling for antiretroviral therapy use, mental health treatment, medication adherence, substance abuse, clinical indicators, and demographic factors. One thousand seven hundred sixteen HIV-seropositive women completed semiannual visits from 1994 through 2001 to clinics at 6 sites. Multivariate Cox and logistic regression analyses estimated time to AIDS-related death and depressive symptom severity. After we controlled for all other factors, AIDS-related deaths were more likely among women with chronic depressive symptoms, and symptoms were more severe among women in the terminal phase of their illness. Mental health service use was associated with reduced mortality. Treatment for depression is a critically important component of comprehensive care for HIV-seropositive women, especially those with end-stage disease.

References

Feb 27, 1991·JAMA : the Journal of the American Medical Association·B W RovnerM F Folstein
Dec 1, 1993·JAMA : the Journal of the American Medical Association·C G LyketsosH Morgenstern
Oct 21, 1993·The New England Journal of Medicine·S Reichlin
May 1, 1993·Psychological Bulletin·T B Herbert, S Cohen
Mar 21, 1998·Epidemiology·S E BarkanJ Feldman
Jan 27, 2000·JAMA : the Journal of the American Medical Association·C C CarpenterP A Volberding
Jun 3, 2000·Journal of Acquired Immune Deficiency Syndromes : JAIDS·S Low-BeerR S Hogg
Jul 6, 2000·Annals of Internal Medicine·D L PatersonN Singh
Feb 15, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·C A KleebergerL P Jacobson
Mar 23, 2001·JAMA : the Journal of the American Medical Association·J R IckovicsUNKNOWN HIV Epidemiology Research Study Group
Jan 5, 2002·American Journal of Public Health·Judith A CookMary Young
Jan 18, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tracey E WilsonUNKNOWN Women's Interagency HIV Study
Jul 26, 2002·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Judith A CookMary Young

❮ Previous
Next ❯

Citations

Jun 28, 2006·AIDS and Behavior·Frank M KaharuzaJonathan Mermin
Jan 26, 2010·AIDS and Behavior·Nicholas S VogenthalerLisa R Metsch
Nov 27, 2008·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·James L BuescherTsuneya Ikezu
Jul 4, 2006·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Rebecca M SchwartzTracey E Wilson
Oct 8, 2008·Current HIV/AIDS Reports·Judith G Rabkin
Sep 10, 2011·Current HIV/AIDS Reports·Josiah D RichUNKNOWN Centers for AIDS Research—Collaboration on HIV in Corrections (CFAR-CHIC) Working Group
Oct 13, 2010·Social Work in Health Care·Thom ReillyJerry Cade
May 18, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Valérie JournotUNKNOWN ALIZE Study Group
Dec 19, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nancy A HessolMardge H Cohen
Oct 27, 2012·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Russell E PolandEric S Daar
Jun 18, 2009·AIDS Patient Care and STDs·Eduardo E ValverdeClyde McCoy
Feb 7, 2009·AIDS Patient Care and STDs·Suad KapetanovicAndrea Kovacs
May 6, 2008·The Journal of Antimicrobial Chemotherapy·Joshua D HartzellAmy C Weintrob
Aug 2, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jeffrey H SametRichard Saitz
Jun 3, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Audrey L FrenchMardge H Cohen
Nov 20, 2010·Public Health Nursing·Kathryn BorycMiryah Morris
Nov 7, 2006·Journal of General Internal Medicine·Michael S YiJoel Tsevat
Aug 24, 2013·International Journal of STD & AIDS·Seggane MusisiElialilia Okello

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.