Depressive symptoms in acute schizophrenic inpatients

Schizophrenia Research
M NakayaH Suwa

Abstract

Prospective and longitudinal assessment of depressive, positive, and negative symptoms were performed on 86 newly admitted schizophrenic patients. The improvement of depressive symptoms was significantly correlated with the improvement in positive symptoms, but did not correlate with the improvement in negative symptoms. However, depressive symptoms were heterogeneous. Principal components analysis was used to subdivide depressive symptoms into five factors. The improvement of the depression-anxiety factor was significantly associated with improvement of positive symptoms. On the other hand, improvement of negative symptoms was significantly related to that of the reduced activity factor. The change in hypochondriasis had a significant positive correlation with the change in positive symptoms and had a significant negative correlation with the change in negative symptoms. Changes in the other factors of depressive symptoms did not appear to be associated with changes in positive or negative symptoms. The present findings suggest that the various depressive symptoms associated with acute schizophrenia may have different pathophysiological origins.

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Citations

Jul 12, 2002·Psychiatry and Clinical Neurosciences·Makoto NakayaKenichi Ohmori
Jan 22, 2008·Psychiatry Research·Makoto Nakaya, Kenichi Ohmori
Feb 22, 2012·Journal of Psychiatric and Mental Health Nursing·B Scholes, C R Martin
Jul 21, 2004·Psychiatry Research·Alessandro SerrettiEnrico Smeraldi
Dec 5, 2012·Journal of Behavior Therapy and Experimental Psychiatry·J J RicarteL Ros
Feb 5, 2008·The International Journal of Neuropsychopharmacology·Arielle D StanfordSarah H Lisanby
Sep 24, 2005·Comprehensive Psychiatry·Paola RoccaFilippo Bogetto
Sep 12, 2006·Psychiatry Research·Makoto Nakaya, Kenich Ohmori
Mar 14, 2018·Acta Psychiatrica Scandinavica·C R KrynickiT R E Barnes
Jun 13, 2002·The Australian and New Zealand Journal of Psychiatry·Paul B FitzgeraldJayashri Kulkarni
Nov 8, 2005·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Hans-Jürgen Möller
Nov 16, 2001·The Journal of Nervous and Mental Disease·J D Huppert, T E Smith
Mar 13, 2002·The Journal of Nervous and Mental Disease·Makoto NakayaKenichi Ohmori

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