Depth perception in Alzheimer's disease

Perceptual and Motor Skills
M F MendezR S Meadows

Abstract

Abnormal depth perception contributes to visuospatial deficits in Alzheimer's disease. Disturbances in stereopsis, motion parallax, and the interpretation of static monocular depth cues may result from neuropathology in the visual cortex. We evaluated 15 patients with mild Alzheimer's disease and 15 controls matched for age, sex, and education on measures of local stereopsis (stereoscopic testing), global stereopsis (random dots), motion parallax (Howard-Dolman apparatus), and monocular depth perception by relative size, interposition, and perspective. Compared to controls, the patients were significantly impaired in over-all depth perception. This impairment was largely due to disturbances in local stereopsis and in the interpretation of depth from perspective, independent of other visuospatial functions. Patients with Alzheimer's disease have disturbed interpretation of monocular as well as binocular depth cues. This information could lead to optic interventions to improve their visual depth perception.

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Citations

Dec 8, 2004·Experimental Brain Research·Zhi Li, Fuchuan Sun
May 22, 2003·Neuropsychologia·Mario F Mendez, Monique M Cherrier
Dec 7, 2013·Survey of Ophthalmology·Radouil Tzekov, Michael Mullan
Jan 22, 2015·International Journal of Environmental Research and Public Health·Chi-Ting HorngYi-Chang Wu
Nov 25, 2004·Perceptual and Motor Skills·E K SkordilisD Koutsouki
Sep 2, 2006·Biological Psychiatry·Isaac SchechterDaniel C Javitt
May 16, 2014·Molecular Neurobiology·Vishal Jindal
Jan 17, 2015·Life Sciences·Wing Lau HoRaymond Chuen-Chung Chang
Jul 16, 2014·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Mark W AlbersLi I Zhang
Dec 14, 2019·Neurology and Therapy·Jennifer NgolabRobert A Rissman
Jan 9, 2019·Acta Neuropathologica Communications·Ian F HarrisonImre Lengyel
Oct 13, 2020·Alzheimer's & Dementia : Translational Research & Clinical Interventions·Keir X X YongSebastian J Crutch
May 19, 2021·European Journal of Ophthalmology·Ioannis-Nikolaos ChalkiasMagda Tsolaki

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