Dequalinium for bacterial vaginosis

Drug and Therapeutics Bulletin

Abstract

Bacterial vaginosis is an infection characterised by overgrowth of anaerobic bacteria in the vagina with an accompanying loss of lactobacilli, and is thought to be the most common cause of abnormal vaginal discharge in women of child-bearing age.(1) Standard treatment for symptomatic bacterial vaginosis consists of a short course of an oral or topical antibiotic.(2) Dequalinium, a topical antiseptic agent, has been available for many years as a treatment for oral infections.(3) A new formulation, dequalinium 10mg vaginal tablets (Fluomizin-Kora Healthcare), was licensed in the UK in June 2015 for the treatment of bacterial vaginosis.(4) Here, we review evidence for the effectiveness and safety of dequalinium vaginal tablets in the management of bacterial vaginosis.

References

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Jul 8, 2008·Drug and Therapeutics Bulletin
Jul 3, 2015·The Primary Care Companion to CNS Disorders·Wales T GeorgeImran S Khawaja
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Aug 18, 2016·Education for Primary Care : an Official Publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors·Jennifer Moffatt

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Citations

May 8, 2020·Journal of Lower Genital Tract Disease·Abigail C MancusoPatricia L Winokur
Feb 13, 2021·Biochemical Pharmacology·Christian Bailly
Feb 26, 2021·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Jordi Antoni VivesAlejandro Doménech
Aug 8, 2020·Gynécologie, Obstétrique, Fertilité & Sénologie·C MauriesS Hamamah

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Bacterial vaginosis can increase the risk of sexually transmitted infections and in rare cases lead to pelvic inflammatory diseases. Discover the latest research on Bacterial Vaginosis here.